ArticleAntimicrobial resistance and infection control2020
Outbreak of Ralstonia mannitolilytica bacteraemia in patients undergoing haemodialysis at a tertiary hospital in Pretoria, South Africa.
Article in Antimicrobial resistance and infection control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed.
- Green biosynthesis of selenium nanoparticles byRSC advances · 2026Article
- Ralstonia pickettii as an emerging pediatric pathogen: a mini-review of current evidence.Frontiers in pediatrics · 2026Review
- A nosocomial outbreak ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025Article
- Epidemiological and genomic characteristics ofMicrobiology spectrum · 2025Article
- Changing Trends of Ralstonia Bacteremia in Patients at a Tertiary Care Center in North India: A 2-Year Retrospective Analysis.The American journal of tropical medicine and hygiene · 2025Observational
- UnveilingAntibiotics (Basel, Switzerland) · 2025Article
- Hidden in Plain Sight: Ralstonia mannitolilytica as a Rare Cause of Urinary Tract Infections.Cureus · 2024Article
- Complete sequence of carbapenem-resistantMicrobiology spectrum · 2024Article
- Influence of host phylogeny and water physicochemistry on microbial assemblages of the fish skin microbiome.FEMS microbiology ecology · 2024Article
- Case report: special imaging features in a uremic patient with intracranial infection caused byFrontiers in medicine · 2024Article
- Bioinformatic Analysis Reveals the Role of Translation Elongation Efficiency Optimisation in the Evolution ofBiology · 2023Article
- Ralstonia mannitolilytica Bacteremia Stemming From Frequent Outpatient Intravenous Injections at a Local Clinic.Cureus · 2023Article
- Decolorization potential of malachite green by Ralstonia mannitolilytica isolated from Indonesian cassava-based fermented food tapai.Archives of microbiology · 2023Article
- Clinical Manifestation ofJournal of Korean medical science · 2023Article
- A urokinase-associated outbreak ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023Article
- Opisthorchis viverrini, Clonorchis sinensis and Opisthorchis felineus liver flukes affect mammalian host microbiome in a species-specific manner.PLoS neglected tropical diseases · 2023Article
- Elucidating the roles of the mammary and gut microbiomes in breast cancer development.Frontiers in oncology · 2023Review
- Bloodstream Infections Caused by Drug ResistantInfection and drug resistance · 2023Article
- Antimicrobial Treatment on a Catheter-Related Bloodstream Infection (CRBSI) Case Due to Transition of a Multi-Drug-ResistantAntibiotics (Basel, Switzerland) · 2022Article
- Waterborne Outbreaks in Hemodialysis Patients and Infection Prevention.Open forum infectious diseases · 2022Article
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5 authors.
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Abstract
backgroundRalstonia species are Gram-negative bacilli of low virulence. These organisms are capable of causing healthcare associated infections through contaminated solutions. In this study, we aimed to determine the source of Ralstonia mannitolilytica bacteraemia in affected patients in a haemodialysis unit.
methodsOur laboratory noted an increase in cases of bacteraemia caused by Ralstonia mannitililytica between May and June 2016. All affected patients underwent haemodialysis at the haemodialysis unit of an academic hospital. The reverse osmosis filter of the haemodialysis water system was found to be dysfunctional. We collected water for culture at various points of the dialysis system to determine the source of the organism implicated. ERIC-PCR was used to determine relatedness of patient and environmental isolates.
resultsSixteen patients were found to have Ralstonia mannitolilytica bacteraemia during the outbreak period. We cultured Ralstonia spp. from water collected in the dialysis system. This isolate and patient isolates were found to have the identical molecular banding pattern.
conclusionsAll patients were septic and received directed antibiotic therapy. There was 1 mortality. The source of the R. mannitolilytica infection in these patients was most likely the dialysis water as the identical organism was cultured from the dialysis water and the patients. The hospital management intervened and repaired the dialysis water system following which no further cases of R. mannitolilytca infections were detected. A multidisciplinary approach is required to control healthcare associated infections such as these. Routine maintenance of water systems in the hospital is essential to prevent clinical infections with R.mannitolilytica.
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