Evidence map›Paper›PMID 32727533›Full record

ArticleRadiation oncology (London, England)2020

Ping Jiang, Konstantine Purtskhvanidze, Gerit Kandzia, Dirk Neumann, Ulf Luetzen, Frank-André Siebert, Johann Roider, Juergen Dunst

Open access · goldAbstract read
In one paragraph

Article in Radiation oncology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Potential of Nanoparticle-Based Phototherapies for Future Treatment of Uveal Melanoma.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Preparation, cytotoxicity, and in vivo antitumor efficacy ofInternational journal of nanomedicine · 2017
    Article
  11. Innovations in brachytherapy.Taiwan journal of ophthalmology
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ping JiangUniversity Clinic for Medical Radiation Physics, Medical Campus Pius-Hospital, Carl von Ossietzky University, Georgstrasse 12, Oldenburg, Germany. fraujiang@hotmail.com.ORCID http://orcid.org/0000-0002-7890-6713
Konstantine PurtskhvanidzeDepartment of Ophthalmology, University Clinic Schleswig-Holstein, Campus Kiel, Germany.
Gerit KandziaDepartment of Radiation Oncology, University Clinic Schleswig-Holstein, Campus Kiel, Germany.
Dirk NeumannDepartment of Radiation Oncology, University Clinic Schleswig-Holstein, Campus Kiel, Germany.
Ulf LuetzenDepartment of Nuclear Medicine, University Clinic Schleswig-Holstein, Campus Kiel, Germany.
Frank-André SiebertDepartment of Radiation Oncology, University Clinic Schleswig-Holstein, Campus Kiel, Germany.
Johann RoiderDepartment of Ophthalmology, University Clinic Schleswig-Holstein, Campus Kiel, Germany.
Juergen DunstUniversity Clinic for Medical Radiation Physics, Medical Campus Pius-Hospital, Carl von Ossietzky University, Georgstrasse 12, Oldenburg, Germany.
University Hospital Schleswig-Holstein · DEPius Hospital Oldenburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate

methodsFrom April 2007 to October 2015, 39 patients with medium sized uveal melanoma were treated with 106 Ru eye plaques brachytherapy. At the time of diagnosis, the mean tumor depth was 3.7 mm (±SD:1.6 mm). The mean dose at the tumor apex was 141.4 Gy (± SD: 12.1 Gy) and 557.7 Gy (± SD: 257.3 Gy) to the sclera.

resultsMean follow-up was 69.5 months (± SD: 53.8 months). Thirty-four patients (87.1%) remained free of recurrence. Twenty-six patients (66.7%) demonstrated a complete tumor regression after a median period of 12 months (3-60 mon.). By the final examination, the visual acuity of 26 patients (66.7%) was better than 20/200, and 12 patients (30.7%) had a visual acuity better than 20/40. Retinopathy was detected in 11 patients (28.2%). After treatments only one patient (5.1%) had active vascular changes by the last examination. Moderate optic neuropathy was observed in 4 patients (10.3%). Cataract development was diagnosed in 21 patients (53.8%), and 16 patients (41%) had bilateral cataract development. Special emphasis was made on patients with larger tumors. Twelve out of the 39 patients had a tumor with a depth of 5 mm or more. There was no significant difference in local control or in side effects between both groups observed.

conclusionsOur study proved

Indexed as

AdultAgedAged, 80 and overBrachytherapyFemaleHumansMaleMelanomaMiddle AgedRadiotherapy DosageRutheniumUveal MelanomaUveal NeoplasmsVisual AcuityRutheniumPlaque brachytherapyRadiotherapyRuthenium

Identifiers

PMID32727533
PMCPMC7392724
OpenAlexW3045890535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.