Evidence map›Paper›PMID 32727525›Full record

ArticleRadiation oncology (London, England)2020

Convolutional neural networks for head and neck tumor segmentation on 7-channel multiparametric MRI: a leave-one-out analysis.

Lars Bielak, Nicole Wiedenmann, Arnie Berlin, Nils Henrik Nicolay, Deepa Darshini Gunashekar, Leonard Hägele, Thomas Lottner, Anca-Ligia Grosu, Michael Bock

Abstract read
In one paragraph

Article in Radiation oncology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. A Coarse-to-Fine Framework for Mid-Radiotherapy Head and Neck Cancer MRI Segmentation.Head and Neck Tumor Segmentation for MR-Guided Applications : First MICCAI Challenge, HNTS-MRG 2024, held in conjunction with MICCAI 2024, Marrakesh, Morocco, October 17, 2024, proceedings · 2025
    Article
  5. MRI-Based Head and Neck Tumor Segmentation Using nnU-Net with 15-Fold Cross-Validation Ensemble.Head and Neck Tumor Segmentation for MR-Guided Applications : First MICCAI Challenge, HNTS-MRG 2024, held in conjunction with MICCAI 2024, Marrakesh, Morocco, October 17, 2024, proceedings · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Automatic segmentation of head and neck primary tumors on MRI using a multi-view CNN.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lars BielakDepartment of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. lars.bielak@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0002-5728-2323
Nicole WiedenmannGerman Cancer Consortium (DKTK), Partner Site Freiburg, Freiburg, Germany.
Arnie BerlinMathWorks, Inc, Novi, MI, USA.
Nils Henrik NicolayGerman Cancer Consortium (DKTK), Partner Site Freiburg, Freiburg, Germany.
Deepa Darshini GunashekarDepartment of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Leonard HägeleDepartment of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Thomas LottnerDepartment of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Anca-Ligia GrosuGerman Cancer Consortium (DKTK), Partner Site Freiburg, Freiburg, Germany.
Michael BockDepartment of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAutomatic tumor segmentation based on Convolutional Neural Networks (CNNs) has shown to be a valuable tool in treatment planning and clinical decision making. We investigate the influence of 7 MRI input channels of a CNN with respect to the segmentation performance of head&neck cancer.

methodsHead&neck cancer patients underwent multi-parametric MRI including T2w, pre- and post-contrast T1w, T2*, perfusion (k

resultsThe CNN segmentation performance scored up to a Dice similarity coefficient (DSC) of 0.65. The network trained without T2* data generally yielded the worst results, with ΔDSC

conclusionsWe developed a method to reduce overall scan times in MRI protocols by prioritizing those sequences that add most unique information for the task of automatic tumor segmentation. The optimized CNNs could be used to aid in the definition of the GTVs in radiotherapy planning, and the faster imaging protocols will reduce patient scan times which can increase patient compliance.

trial registrationThe trial was registered retrospectively at the German Register for Clinical Studies (DRKS) under register number DRKS00003830 on August 20th, 2015.

Indexed as

Neural Networks, ComputerHead and Neck NeoplasmsHumansMultiparametric Magnetic Resonance ImagingRadiotherapy Planning, Computer-AssistedAutomatic tumor segmentationConvolutional neuronal networkMulti-parametric MRIRadiation therapy

Identifiers

PMID32727525
PMCPMC7392704

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.