Evidence map›Paper›PMID 32727522›Full record

ArticleBiomedical engineering online2020

Influence of malformation of right coronary artery originating from the left sinus in hemodynamic environment.

Mengyang Cong, Xingming Xu, Jianfeng Qiu, Shun Dai, Chuanzhi Chen, Xiuqing Qian, Hongbin Zhang, Shengxue Qin, Huihui Zhao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical engineering online, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 14 citations in OpenAlex.

  1. Hypothesized mechanisms of death in swimming: a systematic review.BMC sports science, medicine & rehabilitation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mengyang CongCollege of Mechanical and Electronic Engineering, Shandong University of Science and Technology, Qingdao, 266590, China.
Xingming XuIntelligent Equipment College, Shandong University of Science and Technology, Taian, 271016, China.
Jianfeng QiuDepartment of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, 271016, China.
Shun DaiDepartment of Radiology, Shanghai Tong Ren Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200120, China.
Chuanzhi ChenDepartment of Radiology, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Xiuqing QianDepartment of Biomedical engineering, Capital Medical University, Beijing, 10060, China.
Hongbin ZhangCollege of Mechanical and Electronic Engineering, Shandong University of Science and Technology, Qingdao, 266590, China.
Shengxue QinCollege of Mechanical and Electronic Engineering, Shandong University of Science and Technology, Qingdao, 266590, China. qinshengxue01@163.com.
Huihui ZhaoDepartment of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, 271016, China. HHZhao1029@163.com.ORCID http://orcid.org/0000-0002-3478-7134
Shandong University of Science and Technology · CNShandong First Medical University · CNCapital Medical University · CNShanghai East Hospital · CN

Funding

Academic promotion programme of Shandong First Medical University No. 2019QL009the Taishan Scholars Program of Shandong Province No. TS201712065
6 · The paper itself

Abstract

backgroundThe anomalous origin of the right coronary artery (RCA) from the left coronary artery sinus (AORL) is one of the abnormal origins of the coronary arteries. Most of these issues rarely have any effects on human health, but some individuals may exhibit symptoms, such as myocardial ischemia or even sudden death. Recently, researchers have investigated the AORL through clinical cases, but studies based on computational fluid dynamics (CFD) have rarely been reported. In this study, the hemodynamic changes between the normal origin of the RCA and the AORL are compared based on numerical simulation results.

methodsRealistic three-dimensional (3D) models of the 16 normal right coronary arteries and 26 abnormal origins of the RCAs were constructed, respectively. The blood flow was numerically simulated using the ANSYS software. This study used a one-way fluid-solid coupling finite element model, wherein the blood is assumed to be an incompressible Newtonian fluid, and the vessel is assumed to be made of an isotropic linear elastic material.

resultsThe cross-sectional area differences between the inlet of the normal group and that of the abnormal group were significant (P < 0.0001). Moreover, there were significant differences in the volumetric flow (P = 0.0001) and pressure (P = 0.0002). Positive correlation exists for the ratio of the cross-sectional area of the RCA to the inlet area of the ascending aorta (AAO), and the ratio of the inlet volumetric flow of the RCA to the volumetric flow of the AAO, in the normal (P = 0.0001, r = 0.8178) and abnormal (P = 0.0033, r = 0.6107) groups.

conclusionThis study demonstrates that the cross-sectional area of the AORL inlet may cause ischemia symptoms. The results obtained by this study may contribute to the further understanding of the clinical symptoms of the AORL based on the hemodynamics.

Indexed as

Computer SimulationHemodynamicsCoronary VesselsHydrodynamicsAnomalous right coronary arteryComputational fluid dynamicsPressureStatistical analysisVolumetric flowWall shear stress

Identifiers

PMID32727522
PMCPMC7392689
OpenAlexW3046114200

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.