Evidence map›Paper›PMID 32727476›Full record

ArticleBMC medical imaging2020

Deep semi-supervised learning for brain tumor classification.

Chenjie Ge, Irene Yu-Hua Gu, Asgeir Store Jakola, Jie Yang

Open access · goldAbstract read
In one paragraph

Article in BMC medical imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 97 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Chenjie GeDept. of Electrical Engineering, Chalmers Univ. of Technoloogy, Gothenburg, 41296, Sweden. chenjie@chalmers.se.ORCID 0000-0002-3521-8021
Irene Yu-Hua GuDept. of Electrical Engineering, Chalmers Univ. of Technoloogy, Gothenburg, 41296, Sweden.
Asgeir Store JakolaSahlgrenska University Hospital and Inst. of Neuroscience and Physiology, Sahlgrenska Academy, Gothenburg, 41345, Sweden.
Jie YangInst. of Image Processing and Pattern Recognition, Shanghai Jiao Tong Univ., Shanghai, 200240, China.
Chalmers University of Technology · SESahlgrenska University Hospital · SEShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis paper addresses issues of brain tumor, glioma, classification from four modalities of Magnetic Resonance Image (MRI) scans (i.e., T1 weighted MRI, T1 weighted MRI with contrast-enhanced, T2 weighted MRI and FLAIR). Currently, many available glioma datasets often contain some unlabeled brain scans, and many datasets are moderate in size.

methodsWe propose to exploit deep semi-supervised learning to make full use of the unlabeled data. Deep CNN features were incorporated into a new graph-based semi-supervised learning framework for learning the labels of the unlabeled data, where a new 3D-2D consistent constraint is added to make consistent classifications for the 2D slices from the same 3D brain scan. A deep-learning classifier is then trained to classify different glioma types using both labeled and unlabeled data with estimated labels. To alleviate the overfitting caused by moderate-size datasets, synthetic MRIs generated by Generative Adversarial Networks (GANs) are added in the training of CNNs.

resultsThe proposed scheme has been tested on two glioma datasets, TCGA dataset for IDH-mutation prediction (molecular-based glioma subtype classification) and MICCAI dataset for glioma grading. Our results have shown good performance (with test accuracies 86.53% on TCGA dataset and 90.70% on MICCAI dataset).

conclusionsThe proposed scheme is effective for glioma IDH-mutation prediction and glioma grading, and its performance is comparable to the state-of-the-art.

Indexed as

Brain NeoplasmsDatabases, FactualDeep LearningGliomaHumansIsocitrate DehydrogenaseMutationNeoplasm GradingNeural Networks, ComputerRadiographic Image Interpretation, Computer-AssistedSupervised Machine LearningIsocitrate DehydrogenaseDeep learningGliomaGradingMolecular-based brain tumor classificationMRISemi-supervised learning

Identifiers

PMID32727476
PMCPMC7391541
OpenAlexW3045522357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.