Evidence map›Paper›PMID 32727457›Full record

ArticleBMC surgery2020

In-hospital mortality and failure to rescue following hepatobiliary surgery in Germany - a nationwide analysis.

Christian Krautz, Christine Gall, Olaf Gefeller, Ulrike Nimptsch, Thomas Mansky, Maximilian Brunner, Georg F Weber, Robert Grützmann, Stephan Kersting

Abstract read
In one paragraph

Article in BMC surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Hepatopancreaticobiliary Surgical Outcomes at a Community Hospital.Hawai'i journal of health & social welfare · 2022
    Article
  13. [Minimum case volumes from the perspective of university providers].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2022
    Review
  14. [Minimum volume requirements-perspective of a tertiary care hospital].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christian KrautzUniversitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Klinik für Allgemein- und Viszeralchirurgie, Krankenhausstraße 12, 91054, Erlangen, Germany. christian.krautz@uk-erlangen.de.ORCID http://orcid.org/0000-0002-2537-5824
Christine GallFriedrich-Alexander-Universität Erlangen-Nürnberg, Institut für Medizininformatik, Biometrie und Epidemiologie, Waldstraße 6, 91054, Erlangen, Germany.
Olaf GefellerFriedrich-Alexander-Universität Erlangen-Nürnberg, Institut für Medizininformatik, Biometrie und Epidemiologie, Waldstraße 6, 91054, Erlangen, Germany.
Ulrike NimptschTechnische Universität Berlin, Department of Health Care Management, Straße des 17. Juni 135, 10623, Berlin, Germany.
Thomas ManskyTechnische Universität Berlin, Department for Structural Advancement and Quality Management in Health Care, Straße des 17. Juni 135, 10623, Berlin, Germany.
Maximilian BrunnerUniversitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Klinik für Allgemein- und Viszeralchirurgie, Krankenhausstraße 12, 91054, Erlangen, Germany.
Georg F WeberUniversitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Klinik für Allgemein- und Viszeralchirurgie, Krankenhausstraße 12, 91054, Erlangen, Germany.
Robert GrützmannUniversitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Klinik für Allgemein- und Viszeralchirurgie, Krankenhausstraße 12, 91054, Erlangen, Germany.
Stephan KerstingUniversitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Klinik für Allgemein- und Viszeralchirurgie, Krankenhausstraße 12, 91054, Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent observational studies on volume-outcome associations in hepatobiliary surgery were not designed to account for the varying extent of hepatobiliary resections and the consequential risk of perioperative morbidity and mortality. Therefore, this study aimed to determine the risk-adjusted in-hospital mortality for minor and major hepatobiliary resections at the national level in Germany and to examine the effect of hospital volume on in-hospital mortality, and failure to rescue.

methodsAll inpatient cases of hepatobiliary surgery (n = 31,114) in Germany from 2009 to 2015 were studied using national hospital discharge data. After ranking hospitals according to increasing hospital volumes, five volume categories were established based on all hepatobiliary resections. The association between hospital volume and in-hospital mortality following minor and major hepatobiliary resections was evaluated by multivariable regression methods.

resultsMinor hepatobiliary resections were associated with an overall mortality rate of 3.9% and showed no significant volume-outcome associations. In contrast, overall mortality rate of major hepatobiliary resections was 10.3%. In this cohort, risk-adjusted in-hospital mortality following major resections varied widely across hospital volume categories, from 11.4% (95% CI 10.4-12.5) in very low volume hospitals to 7.4% (95% CI 6.6-8.2) in very high volume hospitals (risk-adjusted OR 0.59, 95% CI 0.41-0.54). Moreover, rates of failure to rescue decreased from 29.38% (95% CI 26.7-32.2) in very low volume hospitals to 21.38% (95% CI 19.2-23.8) in very high volume hospitals.

conclusionsIn Germany, patients who are undergoing major hepatobiliary resections have improved outcomes, if they are admitted to higher volume hospitals. However, such associations are not evident following minor hepatobiliary resections. Following major hepatobiliary resections, 70-80% of the excess mortality in very low volume hospitals was estimated to be attributable to failure to rescue.

Indexed as

Failure to Rescue, Health CareHospital MortalityAgedDigestive System DiseasesDigestive System Surgical ProceduresFemaleGermanyHepatectomyHospitals, High-VolumeHospitals, Low-VolumeHumansMaleMiddle Aged

Identifiers

PMID32727457
PMCPMC7388497

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.