Evidence map›Paper›PMID 32727411›Full record

ReviewBMC nephrology2020

Diffuse large B cell lymphoma in a preceding IgG4-related disease with kidney restricted lambda light chain expression: case report and literature review.

Hui Wang, Tao Su, Lei Kang, Li Yang, Suxia Wang

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hui WangRenal division, Department of medicine, Peking University First Hospital, Peking University Institute of Nephrology, Beijing, China.
Tao SuRenal division, Department of medicine, Peking University First Hospital, Peking University Institute of Nephrology, Beijing, China. tao.su@bjmu.edu.cn.ORCID 0000-0002-6857-8146
Lei KangDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, China.
Li YangRenal division, Department of medicine, Peking University First Hospital, Peking University Institute of Nephrology, Beijing, China.
Suxia WangRenal division, Department of medicine, Peking University First Hospital, Peking University Institute of Nephrology, Beijing, China.
Peking University · CN

Funding

National Science and Technology Major Projects for major new drugs innovation and development 2017ZX09304028the Beijing Young Scientist Program BJJWZYJH01201910001006
6 · The paper itself

Abstract

backgroundIgG4-related disease (IgG4-RD) is a newly classified but poorly understood immune-medicated systemic disease. It causes potential fibroinflammation in one or more organs, characterized by tumescent organs and marked IgG4-positive plasma cells infiltration in the affected tissues. There have been a few cases revealing close relationship between IgG4-RD and formation of B cell lymphoma. Diffuse large B cell lymphoma (DLBCL) and extranodal marginal zone lymphoma (EMZL) of mucosa-associated lymphoid tissue are the most common sub-types ever described, whereas the exact mechanism remain unclear. CASE PRESENTATION: We report a 64-year old Chinese male who presented chronic kidney disease and was initially diagnosed typical IgG4-RD. Pathological findings revealed there was restricted expression of lambda light chain in the kidney. There was also elevated uptake abnormality observed in

conclusionsConcurrent IgG4-RD with kidney-origin EMZL developing DLBCL has never been reported in the literature. Clinicians should keep in mind that lymphoma may occur in IgG4-RD. The mechanism of lymphomagenesis potential in IgG4-RD needs further study.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsCyclophosphamideDisease ProgressionFluorodeoxyglucose F18GlucocorticoidsHumansImmunoglobulin G4-Related DiseaseImmunoglobulin lambda-ChainsImmunosuppressive AgentsLymphoma, B-Cell, Marginal ZoneLymphoma, Large B-Cell, DiffuseMaleMiddle AgedMissed DiagnosisNephritis, InterstitialPositron Emission Tomography Computed TomographyCyclophosphamideFluorodeoxyglucose F18GlucocorticoidsImmunoglobulin lambda-ChainsImmunosuppressive AgentsPrednisoneRadiopharmaceuticalsCase reportDiffuse large B cell lymphomaExtranodal marginal zone lymphomaIgG4-related diseaseRestricted light chain expression

Identifiers

PMID32727411
PMCPMC7391529
OpenAlexW3045955965

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.