Evidence map›Paper›PMID 32727134›Full record

ArticleMicroorganisms2020

Effects of Vitamin B2 Supplementation in Broilers Microbiota and Metabolome.

Elena Biagi, Carlo Mengucci, Monica Barone, Gianfranco Picone, Alex Lucchi, Pietro Celi, Gilberto Litta, Marco Candela, Gerardo Manfreda, Patrizia Brigidi and 2 more

Abstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
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  5. Review
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Elena BiagiUnit of Holobiont Microbiome and Microbiome Engineering (HolobioME), Department of Pharmacy and Biotechnology (FABIT), Alma Mater Studiorum-University of Bologna, 40126 Bologna, Italy.
Carlo MengucciDepartment of Agricultural and Food Sciences (DISTAL), Alma Mater Studiorum-University of Bologna, 40127 Bologna, Italy.ORCID 0000-0003-0602-3003
Monica BaroneUnit of Holobiont Microbiome and Microbiome Engineering (HolobioME), Department of Pharmacy and Biotechnology (FABIT), Alma Mater Studiorum-University of Bologna, 40126 Bologna, Italy.
Gianfranco PiconeDepartment of Agricultural and Food Sciences (DISTAL), Alma Mater Studiorum-University of Bologna, 40127 Bologna, Italy.ORCID 0000-0001-7932-6692
Alex LucchiDepartment of Agricultural and Food Sciences (DISTAL), Alma Mater Studiorum-University of Bologna, 40127 Bologna, Italy.
Pietro CeliDSM Nutritional Products, Basel, Animal Nutrition and Health, Wurmisweg 576, 4303 Kaiseraugst, Switzerland.
Gilberto LittaDSM Nutritional Products, Basel, Animal Nutrition and Health, Wurmisweg 576, 4303 Kaiseraugst, Switzerland.ORCID 0000-0001-8079-1743
Marco CandelaUnit of Holobiont Microbiome and Microbiome Engineering (HolobioME), Department of Pharmacy and Biotechnology (FABIT), Alma Mater Studiorum-University of Bologna, 40126 Bologna, Italy.
Gerardo ManfredaDepartment of Agricultural and Food Sciences (DISTAL), Alma Mater Studiorum-University of Bologna, 40127 Bologna, Italy.
Patrizia BrigidiInterdepartmental Centre for Industrial AgroFood Research (CIRI-AGRO), Alma Mater Studiorum-University of Bologna, 47521 Cesena, Italy.
Francesco CapozziDepartment of Agricultural and Food Sciences (DISTAL), Alma Mater Studiorum-University of Bologna, 40127 Bologna, Italy.ORCID 0000-0002-5543-2359
Alessandra De CesareDepartment of Veterinary Medical Sciences (DIMEVET), Alma Mater Studiorum-University of Bologna, 40064 Ozzano dell'Emilia, Italy.

Funding

Università di Bologna 77/2018
6 · The paper itself

Abstract

The study of the microbiome in broiler chickens holds great promise for the development of strategies for health maintenance and performance improvement. Nutritional strategies aimed at modulating the microbiota-host relationship can improve chickens' immunological status and metabolic fitness. Here, we present the results of a pilot trial aimed at analyzing the effects of a nutritional strategy involving vitamin B2 supplementation on the ileum, caeca and litter microbiota of Ross 308 broilers, as well as on the metabolic profile of the caecal content. Three groups of chickens were administered control diets and diets supplemented with two different dosages of vitamin B2. Ileum, caeca, and litter samples were obtained from subgroups of birds at three time points along the productive cycle. Sequencing of the 16S rRNA V3-V4 region and NMR metabolomics were used to explore microbiota composition and the concentration of metabolites of interest, including short-chain fatty acids. Vitamin B2 supplementation significantly modulated caeca microbiota, with the highest dosage being more effective in increasing the abundance of health-promoting bacterial groups, including

Indexed as

broilermetabolomemicrobiotashort chain fatty acidsvitamin B2

Identifiers

PMID32727134
PMCPMC7464963

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.