Evidence map›Paper›PMID 32727060›Full record

ArticleAnimals : an open access journal from MDPI2020

Supplemental Herbal Choline Increases 5-hmC DNA on Whole Blood from Pregnant Ewes and Offspring.

José Alejandro Roque-Jiménez, German David Mendoza-Martínez, Anayeli Vázquez-Valladolid, María de la Luz Guerrero-González, Rogelio Flores-Ramírez, Juan Manuel Pinos-Rodriguez, Juan J Loor, Alejandro Enrique Relling, Héctor Aarón Lee-Rangel

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

José Alejandro Roque-JiménezFacultad de Agronomía y Veterinaria, Universidad Autonoma de San Luis Potosí, Carretera Federal 57 Km 14.5, Ejido Palma de la Cruz, Soledad de Graciano Sánchez, San Luis Potosí 78321, Mexico.
German David Mendoza-MartínezDepartamento de Producción Animal, Universidad Autonoma Metropolitana-Xochimilco, CDMX, Mexico City 04960, Mexico.
Anayeli Vázquez-ValladolidFacultad de Agronomía y Veterinaria, Universidad Autonoma de San Luis Potosí, Carretera Federal 57 Km 14.5, Ejido Palma de la Cruz, Soledad de Graciano Sánchez, San Luis Potosí 78321, Mexico.
María de la Luz Guerrero-GonzálezFacultad de Agronomía y Veterinaria, Universidad Autonoma de San Luis Potosí, Carretera Federal 57 Km 14.5, Ejido Palma de la Cruz, Soledad de Graciano Sánchez, San Luis Potosí 78321, Mexico.
Rogelio Flores-RamírezCentro de Investigación Aplicada en Ambiente y Salud, CIACYT-Medicina, Universidad Autonoma de San Luis Potosí, Lomas de San Luis 78210, Mexico.ORCID 0000-0003-2263-6280
Juan Manuel Pinos-RodriguezFacultad de Medicina Veterinaria y Zootecnia, Universidad Veracruzana, Veracruz 91710, Mexico.
Juan J LoorDepartment of Animal Sciences, Division of Nutritional Sciences, University of Illinois, 262 Animal Sciences Laboratory, Urbana, IL 61801, USA.
Alejandro Enrique RellingDepartment of Animal Science, The Ohio State University, Ohio Agricultural Research and Development Center (OARDC), Wooster, OH 44691, USA.
Héctor Aarón Lee-RangelFacultad de Agronomía y Veterinaria, Universidad Autonoma de San Luis Potosí, Carretera Federal 57 Km 14.5, Ejido Palma de la Cruz, Soledad de Graciano Sánchez, San Luis Potosí 78321, Mexico.ORCID 0000-0001-6146-5790
Autonomous University of San Luis Potosí · MXThe Ohio State University · USUniversidad Autónoma Metropolitana · MXUniversidad Veracruzana · MXUniversity of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herbal formulas during pregnancy have been used in developing countries. Despite that, the potential effects on the mother and offspring and whether those supplements elicit epigenetic modifications is still unknown. Therefore, our objectives were to determine the effects of supplemental herbal choline source (BCho) on the percentage of 5-hmC in whole blood from gestating ewes and their offspring, as well as determining the milk quality and growth of the offspring. Thirty-five gestating Rambouillet ewes were randomly assigned to five treatments: T1, supplementation of 4 g per day (gd

Indexed as

early feedingepigenetic changessheep

Identifiers

PMID32727060
PMCPMC7460248
OpenAlexW3044238838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.