Evidence map›Paper›PMID 32727032›Full record

ReviewJournal of clinical medicine2020

The Hidden Burden of Severe Asthma: From Patient Perspective to New Opportunities for Clinicians.

Nicola Scichilone, Peter John Barnes, Salvatore Battaglia, Alida Benfante, Robert Brown, Giorgio Walter Canonica, Gaetano Caramori, Mario Cazzola, Stefano Centanni, Antonella Cianferoni and 16 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 20 institutions in 6 countries.

Nicola ScichiloneDivision of Respiratory Diseases, Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Piazza delle Cliniche 2, 90143 Palermo, Italy.ORCID 0000-0001-6400-6573
Peter John BarnesAirway Disease Section, National Heart & Lung Institute, Imperial College London, Dovehouse Street, London SW3 6LY, UK.ORCID 0000-0002-5122-4018
Salvatore BattagliaDivision of Respiratory Diseases, Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Piazza delle Cliniche 2, 90143 Palermo, Italy.ORCID 0000-0002-2867-917X
Alida BenfanteDivision of Respiratory Diseases, Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Piazza delle Cliniche 2, 90143 Palermo, Italy.
Robert BrownDepartment of Anesthesiology and Critical Care Medicine, Medicine, Department of Medicine, Division of Pulmonary Medicine, Department of Environmental Health and Engineering, Johns Hopkins University, Baltimore, MD 21287, USA.
Giorgio Walter CanonicaPersonalised Medicine Clinic Asthma & Allergy, Humanitas University, Department of Biomedical Sciences, IRCCS Humanitas Research Hospital, Rozzano, 20089 Milan, Italy.
Gaetano CaramoriRespiratory Medicine Unit, Department of Biomedical Sciences, Dentistry and Morphological and Functional Imaging (BIOMORF), University of Messina, 98122 Messina, Italy.ORCID 0000-0002-9807-327X
Mario CazzolaUnit of Respiratory Medicine, Dept. Experimental Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-4895-9707
Stefano CentanniRespiratory Unit, ASST Santi Paolo e Carlo, San Paolo Hospital, Department of Health Sciences, University of Milan, 20142 Milan, Italy.ORCID 0000-0001-9923-535X
Antonella CianferoniPediatrics Department, Perlman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Angelo CorsicoDivision of Respiratory Diseases, IRCCS Policlinico San Matteo Foundation and Department of Internal Medicine and Therapeutics - University of Pavia, 27100 Pavia, Italy.
Giuseppe De CarloThe European Federation of Allergy and Airways Diseases Patients Associations (EFA), 1000 Brussels, Belgium.
Fabiano Di MarcoRespiratory Unit, ASST - Papa Giovanni XXIII Hospital, Bergamo, University of Milan, 24127 Milan, Italy.ORCID 0000-0002-1743-0504
Mina Gaga7th Respiratory Medicine Dept, Asthma Cen, Athens Chest Hospital, 11527 Athens, Greece.ORCID 0000-0002-9949-6012
Catherine HawrylowiczDivision of Asthma, Allergy and Lung Biology, King's College London, Guy's Hospital, London SE1 9RT, UK.
Enrico HefflerPersonalised Medicine Clinic Asthma & Allergy, Humanitas University, Department of Biomedical Sciences, IRCCS Humanitas Research Hospital, Rozzano, 20089 Milan, Italy.
Maria Gabriella MateraUnit of Pharmacology, Dept. Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Andrea MatucciImmunoallergology Unit, Careggi University Hospital, 50139 Florence, Italy.
Pierluigi PaggiaroDepartment of Surgery, Medicine, Molecular Biology and Critical Care, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-1213-2989
Alberto PapiResearch Center on Asthma and COPD, Dept of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Todor PopovClinic of Occupational Diseases, University Hospital Sv. Ivan Rilski, 1431 Sofia, Bulgaria.ORCID 0000-0001-5052-5866
Paola RoglianiUnit of Respiratory Medicine, Dept. Experimental Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0001-7801-5040
Pierachille SantusDivision of Respiratory Diseases, Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, 20157 Milan, Italy.
Paolo SolidoroPneumology Unit U, Cardiovascular and Thoracic Department, AOU Città della Salute e della Scienza di Torino, University of Turin, 10126 Turin, Italy.
Alkis TogiasNational Institute of Allergy and Infectious Diseases, Bethesda, MD 20814, USA.
Louis-Philippe BouletQuebec Heart and Lung Institute, Laval University, Quebec City, QC G1V 0A6, Canada.
University of Palermo · ITHumanitas University · ITUniversity of Milan · ITUniversity of Rome Tor Vergata · ITAzienda Ospedaliero-Universitaria Careggi · ITEuropean Federation of Allergy and Airways Diseases Patients Associations · BEGuy's Hospital · GBImperial College London · GBJohns Hopkins University · USNational Institute of Allergy and Infectious Diseases · USUniversité Laval · CAUniversity Hospital St. Ivan Rilski · BGUniversity of Bergamo · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Ferrara · ITUniversity of Messina · ITUniversity of Pavia · ITUniversity of Pennsylvania · USUniversity of Pisa · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe asthma is an important topic in respiratory diseases, due to its high impact on morbidity and mortality as well as on health-care resources. The many challenges that still exist in the management of the most difficult-to-treat forms of the disease, and the acknowledgement of the existence of unexplored areas in the pathophysiological mechanisms and the therapeutic targets represent an opportunity to gather experts in the field with the immediate goals to summarize current understanding about the natural history of severe asthma and to identify gaps in knowledge and research opportunities, with the aim to contribute to improved medical care and health outcomes. This article is a consensus document from the "International Course on Severe Asthma" that took place in Palermo, Italy, on May 10-11, 2019. Emerging topics in severe asthma were addressed and discussed among experts, with special focus on patient's needs and research opportunities, with the aim to highlight the unanswered questions in the diagnostic process and therapeutic approach.

Indexed as

biomarkerspatient’s perspectiveprecision medicinesevere asthma

Identifiers

PMID32727032
PMCPMC7463666
OpenAlexW3046469499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.