ArticleThe Journal of infectious diseases2020
Epidemiology of Severe Acute Respiratory Syndrome Coronavirus 2 Emergence Amidst Community-Acquired Respiratory Viruses.
Article in The Journal of infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 61 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
61 citing papers in PubMed, 4 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Pooled it
- Worldwide prevalence of microbial agents' coinfection among COVID-19 patients: A comprehensive updated systematic review and meta-analysis.Journal of clinical laboratory analysis · 2022Pooled it
- COVID-19 and Influenza Co-infection: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Viral Coinfection among COVID-19 Patient Groups: An Update Systematic Review and Meta-Analysis.BioMed research international · 2021Pooled it
- Symptom-based diagnostic models for common respiratory viral infections: a machine learning and natural language processing study.Infectious Disease Modelling · 2026Article
- Article
- Three-stage interpretability analysis of influenza virus and meteorological correlation in Jiuquan City, 2016-2025: SARIMAX + TreeSHAP.Frontiers in cellular and infection microbiology · 2026Article
- A study on the climate-driven spatiotemporal dynamics of influenza in Lanzhou spanning the COVID-19 era.Frontiers in cellular and infection microbiology · 2026Article
- Molecular and phylogenetic analysis of influenza A and B viruses circulating in Sri Lanka following the COVID-19 pandemic.Virus genes · 2025Article
- Diagnostic Performance of a Combined Rapid Antigen Test for Detecting SARS-CoV-2, Influenza Virus, and Respiratory Syncytial Virus in Symptomatic Patients in Tertiary Care.Journal of medical virology · 2025Article
- Changes in the epidemic patterns of respiratory pathogens of children in guangzhou, China during the COVID-19 pandemic.BMC infectious diseases · 2025Article
- Epidemiology, co-infection, and seasonal patterns of respiratory tract infections in a tertiary care center in Saudi Arabia between 2021 and 2022.Frontiers in public health · 2025Article
- Influence of respiratory disease experiences on COVID-19 vaccine acceptance: a study from Southeastern Louisiana.Frontiers in public health · 2025Article
- Multicenter Evaluation of the QIAstat-Dx and the BioFire Multiplex Panel Tests for the Detection of Respiratory Pathogens.Journal of medical virology · 2024Article
- Secondary attack rate following on-site isolation of patients with suspected COVID-19 in multiple-bed rooms.Antimicrobial resistance and infection control · 2024Observational
- The Changing Landscape of Respiratory Viruses Contributing to Hospitalizations in Quebec, Canada: Results From an Active Hospital-Based Surveillance Study.JMIR public health and surveillance · 2024Article
- Differential Gene Expression of SARS-CoV-2 Positive Bronchoalveolar Lavages: A Case Series.Pathobiology : journal of immunopathology, molecular and cellular biology · 2024Article
- SARS-CoV-2 co-detection with influenza and human respiratory syncytial virus in Ethiopia: Findings from the severe acute respiratory illness (SARI) and influenza-like illness (ILI) sentinel surveillance, January 01, 2021, to June 30, 2022.PLOS global public health · 2024Article
- Impact of the COVID-19 pandemic on non-COVID-19 community-acquired pneumonia: a retrospective cohort study.BMJ open respiratory research · 2023Article
- Impact of SARS-CoV-2-Related Hygiene Measures on Community-Acquired Respiratory Virus Infections in Lung Transplant Recipients in Switzerland.Medicina (Kaunas, Lithuania) · 2023Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
18 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China as the cause of coronavirus disease 2019 in December 2019 and reached Europe by late January 2020, when community-acquired respiratory viruses (CARVs) are at their annual peak. We validated the World Health Organization (WHO)-recommended SARS-CoV-2 assay and analyzed the epidemiology of SARS-CoV-2 and CARVs.
methodsNasopharyngeal/oropharyngeal swabs (NOPS) from 7663 patients were prospectively tested by the Basel S-gene and WHO-based E-gene (Roche) assays in parallel using the Basel N-gene assay for confirmation. CARVs were prospectively tested in 2394 NOPS by multiplex nucleic acid testing, including 1816 (75%) simultaneously for SARS-CoV-2.
resultsThe Basel S-gene and Roche E-gene assays were concordant in 7475 cases (97.5%) including 825 (11%) SARS-CoV-2 positives. In 188 (2.5%) discordant cases, SARS-CoV-2 loads were significantly lower than in concordant positive ones and confirmed in 105 (1.4%). Adults were more frequently SARS-CoV-2 positive, whereas children tested more frequently CARV positive. CARV coinfections with SARS-CoV-2 occurred in 1.8%. SARS-CoV-2 replaced CARVs within 3 weeks, reaching 48% of all detected respiratory viruses followed by rhinovirus/enterovirus (13%), influenza virus (12%), coronavirus (9%), respiratory syncytial virus (6%), and metapneumovirus (6%).
conclusionsWinter CARVs were dominant during the early SARS-CoV-2 pandemic, impacting infection control and treatment decisions, but were rapidly replaced, suggesting competitive infection. We hypothesize that preexisting immune memory and innate immune interference contribute to the different SARS-CoV-2 epidemiology among adults and children.
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