Evidence map›Paper›PMID 32726334›Full record

ArticlePloS one2020

Occupational cohort study of current and former workers exposed to chrysotile in mine and processing facilities in Asbest, the Russian Federation: Cohort profile of the Asbest Chrysotile Cohort study.

Joachim Schüz, Igor Bukhtiyarov, Ann Olsson, Monika Moissonnier, Evgenia Ostroumova, Eleonora Feletto, Sara J Schonfeld, Graham Byrnes, Iraklii Tskhomariia, Valerie McCormack and 5 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 5 countries.

Joachim SchüzInternational Agency for Research on Cancer (IARC/WHO), Lyon, France.ORCID 0000-0001-9687-2134
Igor BukhtiyarovFederal State Budgetary Scientific Institution "Izmerov Research Institute of Occupational Health" (IRIOH), Moscow, the Russian Federation.
Ann OlssonInternational Agency for Research on Cancer (IARC/WHO), Lyon, France.
Monika MoissonnierInternational Agency for Research on Cancer (IARC/WHO), Lyon, France.
Evgenia OstroumovaInternational Agency for Research on Cancer (IARC/WHO), Lyon, France.
Eleonora FelettoInternational Agency for Research on Cancer (IARC/WHO), Lyon, France.
Sara J SchonfeldInternational Agency for Research on Cancer (IARC/WHO), Lyon, France.
Graham ByrnesInternational Agency for Research on Cancer (IARC/WHO), Lyon, France.
Iraklii TskhomariiaFederal State Budgetary Scientific Institution "Izmerov Research Institute of Occupational Health" (IRIOH), Moscow, the Russian Federation.
Valerie McCormackInternational Agency for Research on Cancer (IARC/WHO), Lyon, France.
Kurt StraifInternational Agency for Research on Cancer (IARC/WHO), Lyon, France.
Sergey KashanskiyYekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Yekaterinburg, the Russian Federation.
Tatiana MorozovaI.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, the Russian Federation.
Hans KromhoutInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0002-4233-1890
Evgeny KovalevskiyFederal State Budgetary Scientific Institution "Izmerov Research Institute of Occupational Health" (IRIOH), Moscow, the Russian Federation.ORCID 0000-0001-5166-6871
Centre international de recherche sur le cancer · FRSechenov University · RUEkaterinburg Research Institute of Viral Infections · RUNational Institutes of Health · USThe Federal State Budgetary Scientific Institution "Izmerov Research Institute of Occupational Health" · RUUtrecht University · NL

Funding

World Health Organization 001
6 · The paper itself

Abstract

A historical cohort study in workers occupationally exposed to chrysotile was set up in the town of Asbest, the Russian Federation, to study their cause-specific mortality, with a focus on cancer. Chrysotile has different chemical and physical properties compared with other asbestos fibres; therefore it is important to conduct studies specifically of chrysotile and in different geographical regions to improve the knowledge about its carcinogenicity. Setting was the town of Asbest, Sverdlovsk oblast, the Russian Federation. Participants were all current and former employees with at least one year of employment between 1/1/1975 and 31/12/2010 in the mine, enrichment factories, auto-transport and external rail transportation departments, the central laboratory, and the explosives unit of the company. Of the 35,837 cohort members, 12,729 (35.5%) had died (2,373 of them of cancer, including 10 of mesothelioma), 18,799 (52.5%) were known to be alive at the end of the observation period (2015), and 4,309 (12.0%) were censored before the end of 2015. Mean follow-up duration was 21.7 years in men and 25.9 years in women. The mean age at death was 59.4 years in men and 66.5 years in women. This is the largest occupational cohort of chrysotile workers to date, and the only one with a large proportion of exposed female workers.

Indexed as

AdultAsbestosAsbestos, SerpentineCohort StudiesFemaleHumansLung NeoplasmsMaleMesotheliomaMesothelioma, MalignantMiddle AgedOccupational DiseasesOccupational ExposureRussiaAsbestosAsbestos, Serpentine

Identifiers

PMID32726334
PMCPMC7390538
OpenAlexW3045680372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.