ArticleObesity (Silver Spring, Md.)2020
Retinal Vascular Tortuosity and Diameter Associations with Adiposity and Components of Body Composition.
Article in Obesity (Silver Spring, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06888765 (The Impact of Changes in Body Composition on the Retina and Choroid), which is not on this map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Impact of Changes in Body Composition on the Retina and Choroid
Who cites it
18 citing papers in PubMed, 24 citations in OpenAlex.
- Randomized 20-year infancy-onset dietary intervention, life-long cardiovascular risk factors and retinal microvasculature.European heart journal · 2024Trial
- Dyslipidemia and Retinal Microvascular Health in Children and Adolescents: A Systematic Review.Children (Basel, Switzerland) · 2026Review
- Retinal Microvascular Calibres and Body Fat Indices in Young Adults.International journal of environmental research and public health · 2026Article
- Relationship Between Retinal Vascular Measurements and Anthropometric Indices in Patients Diagnosed with Persistent COVID-19.Journal of clinical medicine · 2025Article
- The association between retinal artery to vein ratio and fat distribution: a population-based cross-sectional study.BMC ophthalmology · 2025Article
- Factors Associated With Retinal Vessel Traits in the Canadian Longitudinal Study on Aging.Investigative ophthalmology & visual science · 2025Article
- Longitudinal associations of retinal vessel morphology with intraocular pressure and blood pressure at follow-up visit-Findings from a Danish eye and vision cohort, Project FOREVER.Acta ophthalmologica · 2025Article
- Genome-wide Association Studies of Retinal Vessel Tortuosity Identify Numerous Novel Loci Revealing Genes and Pathways Associated With Ocular and Cardiometabolic Diseases.Ophthalmology science · 2023Article
- Cohort profile: rationale and methods of UK Biobank repeat imaging study eye measures to study dementia.BMJ open · 2023Article
- GWAS on retinal vasculometry phenotypes.PLoS genetics · 2023Article
- Automated analysis of vessel morphometry in retinal images from a Danish high street optician setting.PloS one · 2023Article
- Artificial intelligence-enabled retinal vasculometry for prediction of circulatory mortality, myocardial infarction and stroke.The British journal of ophthalmology · 2022Article
- Retinal microvascular associations with cardiometabolic risk factors differ by diabetes status: results from the UK Biobank.Diabetologia · 2022Article
- Effects of Dried Onion Powder and Quercetin on Obesity-Associated Hepatic Menifestation and Retinopathy.International journal of molecular sciences · 2022Article
- Retinal microvasculature and time to pregnancy in a multi-ethnic pre-conception cohort in Singapore.Human reproduction (Oxford, England) · 2021Article
- Macular Vascular Geometry Changes With Sex and Age in Healthy Subjects: A Fundus Photography Study.Frontiers in medicine · 2021Article
- Retinal vasculometry associations with cognition status in UK Biobank.Alzheimer's & dementia (Amsterdam, Netherlands)Article
- A narrative review of retinal vascular parameters and the applications (Part I): Measuring methods.Brain circulationReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
objectiveThe aim of this study was to assess whether adiposity or body composition relates to microvascular characteristics of the retina, indicative of cardiometabolic function.
methodsA fully automated QUARTZ software processed retinal images from 68,550 UK Biobank participants (aged 40-69 years). Differences in retinal vessel diameter and tortuosity with body composition measures from the Tanita analyzer were obtained by using multilevel regression analyses adjusted for age, sex, ethnicity, clinic, smoking, and Townsend deprivation index.
resultsVenular tortuosity and diameter increased by approximately 2% (P < 10
conclusionsThis demonstrates, on an unprecedented scale, that venular tortuosity and diameter are more strongly associated with adiposity, whereas arteriolar diameter relates more strongly to fat-free mass. Different attributes of the retinal microvasculature may reflect distinct roles of body composition and fatness on the cardiometabolic system.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.