ArticleClinical cardiology2020
Birthweight predicts adult cardiovascular disorders: Population based cross sectional survey.
Article in Clinical cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Cerebral Small Vessel Disease: Early-Life Antecedents and Long-Term Implications for the Brain, Aging, Stroke, and Dementia.Hypertension (Dallas, Tex. : 1979) · 2024Review
- Birthweight predicts glomerular filtration rate in adult-life: population based cross sectional study.Renal failure · 2021Article
- Does Prenatal Exposure to CNS Stimulants Increase the Risk of Cardiovascular Disease in Adult Offspring?Frontiers in cardiovascular medicine · 2021Review
- Birthweight predicts adult cardiovascular disorders: Population based cross sectional survey.Clinical cardiology · 2020Article
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiovascular disease (CVD) is the primary cause of death in the developed-countries and mostly in the poorer areas of the country, and in lower income-groups. HYPOTHESIS: Birthweight predicts adult development of angina, coronary heart disease, stroke, and combination of all CVD.
methodsThe AusDiab is a cross-sectional study of Australians aged 25 years or over. Data on age, sex, previous-CVD, smoking-status, alcohol-intake, time-spent on watching television and physical-activity, total house-income, dwelling-type and education-level were collected by interviewer- administered-questionnaires.
resultsFour thousand five hundred and two had birthweights (mean (SD) of 3.4(0.7) kg). Females in the lowest birthweight-quintile were at least 1.23, 1.48, 1.65, and 1.23 times more likely to have angina, CAD, stroke, and CVS compared to the referent group ≥3.72 kg with P = .123, .09, .099, and 0.176, respectively. Similarly, males in the lowest-birthweight-quintile were 1.23, 1.30, 1.39, and 1.26 times more likely to have angina, CAD, stroke, and CVS compared to the referent-group ≥4.05 kg with P = .231, .087, .102, and .123, respectively. Females with low birth weight (LBW) were at least 1.39, 1.40, 2.30, and 1.47 times more likely to have angina, CAD, stroke and CVS compared to those ≥2.5 kg with P = .06, .19, .03, and .13, respectively. Similarly, males with LBW were 1.76, 1.48, 3.34, and 1.70 times more likely to have angina, CAD, stroke, and CVS compared to those ≥2.5 kg with P = .14, .13, .03, and .08, respectively.
conclusionthere was a negative relationship between birth weight and angina, CAD, stroke, and the overall CVS. It would be prudent, to adopt policies of intensified whole of life surveillance of lower-birthweight people, anticipating this risk.
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