Evidence map›Paper›PMID 32725604›Full record

Trial reportEmergency radiology2021

Is point of care renal function testing reliable screening pre-IV contrast administration?

Namit Mathur, Zhong X Lu, Lisa MacKay, Theodore Lau, Ahilan Kuganesan, Kenneth K Lau

Abstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Emergency radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Namit MathurEmergency Department, Monash Health, Clayton, Victoria, Australia. mathurnamit@yahoo.com.au.ORCID https://orcid.org/0000-0002-3827-2461
Zhong X LuMonash Pathology, Monash Health, Clayton, Victoria, Australia.
Lisa MacKayMonash Pathology, Monash Health, Clayton, Victoria, Australia.
Theodore LauMonash Imaging, Monash Health, Clayton, Victoria, Australia.
Ahilan KuganesanMonash Imaging, Monash Health, Clayton, Victoria, Australia.
Kenneth K LauDepartment of Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.
Monash Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIntravenous iodinated contrast is a commonly used diagnostic aid to improve image quality on computed tomography. There exists a small risk of post-contrast acute kidney injury in patients receiving IV contrast. One of the biggest risk factors for developing PC-AKI is the presence of pre-existing renal dysfunction, making it important to measure the renal function prior to contrast administration. Point of care (POC) devices offer a quick estimation of renal function, potentially improving workflows in radiology departments.

methodTwo POC devices were evaluated, the Nova StatSensor and Abbott iSTAT. Patients undergoing routine radiological investigations had blood collected and analysed by a POC method and the laboratory method (Beckman AU5800). The two values were analysed and compared. Renal function was calculated using eGFR via the CKD-EPI result. eGFR values were stratified as high risk (eGFR < 30), moderate risk (eGFR 30-59) and low risk (eGFR ≥ 60).

resultsOne hundred eighty-six patients were included in the study. One hundred one patients underwent the Abbott iSTAT analysis, 139 patients underwent Nova StatSensor analysis, and 53 had both. Statistical analysis revealed that the StatSensor R

conclusionPOC devices are moderately accurate at detecting renal impairment in patients undergoing radiological investigations. They seem to be a good screening tool; however, any low eGFR values should be further examined.

Indexed as

Kidney Function TestsPoint-of-Care TestingTomography, X-Ray ComputedAdultAustraliaContrast MediaCreatinineFemaleGlomerular Filtration RateHumansKidney DiseasesMaleRisk FactorsContrast MediaCreatinineContrast-enhanced imagingContrast-induced kidney injuryCreatinineDiagnostic imagingEstimated glomerular filtration ratePoint-of-care testing

Identifiers

PMID32725604
OpenAlexW3046037459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.