Evidence map›Paper›PMID 32725541›Full record

ArticleDer Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft2021

[Extraction of features from clinical routine data using text mining].

Bastian Grundel, Marc-Antoine Bernardeau, Holger Langner, Christoph Schmidt, Daniel Böhringer, Marc Ritter, Paul Rosenthal, Andrea Grandjean, Stefan Schulz, Philipp Daumke and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Enhancing diagnostic precision for rare diseases using case-based reasoning.Journal of the American Medical Informatics Association : JAMIA · 2026
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Bastian GrundelKlinik und Poliklinik für Augenheilkunde, Universitätsmedizin Greifswald, Greifswald, Deutschland.
Marc-Antoine BernardeauKlinik und Poliklinik für Augenheilkunde, Universitätsmedizin Greifswald, Greifswald, Deutschland.
Holger LangnerProfessur Medieninformatik, Hochschule Mittweida, Mittweida, Deutschland.
Christoph SchmidtInstitute for Visual and Analytic Computing, Universität Rostock, Rostock, Deutschland.ORCID http://orcid.org/0000-0002-5358-0673
Daniel BöhringerKlinik für Augenheilkunde, Universitätsklinikum Freiburg, Medizinische Fakultät, Universität Freiburg, Freiburg, Deutschland.
Marc RitterProfessur Medieninformatik, Hochschule Mittweida, Mittweida, Deutschland.
Paul RosenthalInstitute for Visual and Analytic Computing, Universität Rostock, Rostock, Deutschland.ORCID http://orcid.org/0000-0001-9409-8931
Andrea GrandjeanAverbis GmbH, Freiburg, Deutschland.
Stefan SchulzAverbis GmbH, Freiburg, Deutschland.ORCID http://orcid.org/0000-0001-7222-3287
Philipp DaumkeAverbis GmbH, Freiburg, Deutschland. philipp.daumke@averbis.com.ORCID http://orcid.org/0000-0003-4437-4840
Andreas StahlKlinik und Poliklinik für Augenheilkunde, Universitätsmedizin Greifswald, Greifswald, Deutschland.ORCID http://orcid.org/0000-0002-8013-7597
Averbis (Germany) · DEHochschule Mittweida · DEUniversity of Rostock · DEUniversity Medical Center Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnti-VEGF drugs are currently used to treat macular diseases. This has led to a wealth of additional data, which could help understand and predict treatment courses; however, this information is usually only available in free text form.

objectiveA retrospective study was designed to analyze how far interpretable information can be obtained from clinical texts by automated extraction. The aim was to assess the suitability of a text mining method that was customized for this purpose. MATERIAL AND

methodsData on 3683 patients were available, including 40,485 discharge letters. Some of the data of interest, e.g. visual acuity (VA), intraocular pressure (IOP) and accompanying diagnoses, were not only recorded textually but also entered in a database and could thus serve as a gold standard for text analysis. The text was analyzed using the Averbis Health Discovery text mining platform. To optimize the extraction task, rule knowledge and a German language technical vocabulary linked to the international medical terminology standard systematized nomenclature of medicine (SNOMED CT) was manually added.

resultsThe correspondence between extracted data and the structured database entries is described by the F1 value. There was agreement of 94.7% for VA, 98.3% for IOP and 94.7% for the accompanying diagnoses. Manual analysis of noncorresponding cases showed that in 50% text content did not match the database content for various reasons. After an adjustment, F1 values 1-3% above the previously determined values were obtained.

conclusionText mining procedures are very well suited for the considered discharge letter corpus and the problem described in order to extract contents from clinical texts in a structured manner for further evaluation.

Indexed as

Data MiningSystematized Nomenclature of MedicineDatabases, FactualElectronic Health RecordsHumansIntraocular PressureRetrospective StudiesDecision support systemsElectronic health recordsMacular degenerationNatural language processingSystematized nomenclature of medicine

Identifiers

PMID32725541
OpenAlexW3045597768

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.