ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2021
Pineal region tumors: an entity with crucial anatomical nuances.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Metastases in the Pineal Region: A Systematic Review of Clinical Features, Management Strategies, and Survival Outcomes.World neurosurgery · 2022Pooled it
- Multimodal clinical-radiomic-deep learning model for preoperative classification of pediatric pineal region tumors.Neuroradiology · 2026Article
- Optic nerve sheath diameter correlates with both success and failure of hydrocephalus treatment in pediatric patients with pineal region lesions.Acta neurochirurgica · 2024Article
- Survival and Malignant Transformation of Pineal Parenchymal Tumors: A 30-Year Retrospective Analysis in a Single-Institution.Brain tumor research and treatment · 2023Article
- Neuroendoscopy in the management of pineal region tumours in children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Supratentorial Pediatric Midline Tumors and Tumor-like Lesions: Clinical Spectrum, Natural History and Treatment Options.Children (Basel, Switzerland) · 2022Review
- Interhemispheric transcallosal intervenous approach to a pineal region tumor.Neurosurgical focus: Video · 2021Article
- Pineal region tumors: a complement with imaging nuances.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Endoscopic resection of a low-grade ependymoma of the pineal region.Surgical neurology international · 2021Article
- A 2-step prediction model for diagnosis of germinomas in the pineal region.Neuro-oncology advancesArticle
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5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeIntra-axial "pineal region" tumors include pineal, tectal, and aqueductal tumors. All three tumor subgroups cause obstruction of the aqueduct; however, they differ in radiological nuances, pathology, differential diagnosis, and treatment. The goal of this manuscript is to describe the radiological, clinical, and pathological nuances that differentiate between these subgroups.
methodsAll patients with intra-axial pineal region tumors were analyzed retrospectively, including demographics, radiological characteristics, pathology, treatment, and outcome.
resultsForty-nine patients (1-69 years of age) were included: 19 pineal, 10 tectal, 10 aqueductal, 4 periaqueductal, and 6 complex. The 3 main subgroups differed in various radiological and anatomical nuances. Age and gender did not differ between groups. Other factors that did not differ between groups included T1 and T2 signals, presence of blood products, a normally located (non-displaced) tectum, anterior tectal displacement, thalamic involvement, and presence of hydrocephalus. The pathological spectrum differed between the 3 main subgroups, as well as the surgical treatment, and outcome.
conclusionsDespite sharing a close anatomical location, as well as all causing obstruction of the aqueduct with secondary hydrocephalus, the differential diagnosis, diagnostic methods, and possible treatment and surgical options differ between the various subgroups. Anatomical nuances are described to better delineate the various tumor subgroups and recommend specific treatment approaches.
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