ArticleParasitology research2020
Hepatozoon canis in hunting dogs from Southern Italy: distribution and risk factors.
Article in Parasitology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Host-Specific Circulation and Molecular Diversity ofAnimals : an open access journal from MDPI · 2026Article
- Molecular Genetics ofEcology and evolution · 2026Article
- Challenging the Clinical Paradigm of Hepatozoon canis: A Primary Pathogen Causing Clinically Significant Disease at Low Parasitaemia and a Chronic Inflammatory State.Veterinary medicine and science · 2026Article
- Phylogenetic and histopathological characterization of putative Hepatozoon ophisauri-like lineages in rodents from Italy.Acta parasitologica · 2026Article
- Hepatozoon martis in Italy: first evidence based on histopathological characterization and molecular confirmation in Martes foina.Parasites & vectors · 2026Article
- Molecular identification and associated risk factors of Hepatozoon canis among dogs visiting veterinary clinics in Tehran, Iran.BMC veterinary research · 2025Article
- Hepatozoon infections in domestic and wild Carnivora: etiology, prevalence, clinical disease, diagnosis and treatment, and redescription of Hepatozoon silvestris, H. martis, and H. ursi.Parasites & vectors · 2025Review
- A review of Hepatozoonosis caused byJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024Review
- Molecular detection of Hepatozoon canis in dogs from Ibagué, Tolima.The Journal of veterinary medical science · 2024Article
- Molecular Survey ofVeterinary sciences · 2023Article
- Autochthonous infection with Ehrlichia Canis and Hepatozoon Canis in dogs from Serbia.Veterinary medicine and science · 2023Article
- First molecular detection ofFrontiers in veterinary science · 2023Article
- Clinical, diagnostic and epidemiological implications of Hepatozoon spp., Babesia spp. and Leishmania infantum infection in cats and dogs in a Mediterranean periurban setting.Parasitology research · 2023Article
- Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova.Pathogens (Basel, Switzerland) · 2022Article
- Distribution of Tick-Borne Pathogens in Domestic Animals and Their Ticks in the Countries of the Mediterranean Basin between 2000 and 2021: A Systematic Review.Microorganisms · 2022Article
- First Record ofMicroorganisms · 2022Article
- Concomitant Infections With Canine Parvovirus Type 2 and Intracellular Tick-Borne Pathogens in Two Puppy Dogs.Frontiers in veterinary science · 2022Article
- Potential Role ofPathogens (Basel, Switzerland) · 2021Article
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatozoon canis is a hemoprotozoan organism that infects domestic and wild carnivores throughout much of Europe. The parasite is mainly transmitted through the ingestion of infected ticks containing mature oocysts. The aims of the present survey were to determine the prevalence of H. canis in hunting dogs living in Southern Italy and to assess potential infection risk factors. DNA extracted from whole blood samples, collected from 1433 apparently healthy dogs living in the Napoli, Avellino, and Salerno provinces of Campania region (Southern Italy), was tested by a quantitative real-time polymerase chain reaction (qPCR) assay to amplify H. canis. Furthermore, the investigated dog population was also screened by qPCR for the presence of Ehrlichia canis, a major tick-borne pathogen in Southern Italy, in order to assess possible co-infections. Two hundred dogs were H. canis PCR-positive, resulting in an overall prevalence of 14.0% (CI 12.2-15.9). Breed category (P < 0.0001), hair coat length (P = 0.015), and province of residence (P < 0.0001) represented significant risk factors for H. canis infection. The presence of H. canis DNA was also significantly associated with E. canis PCR positivity (P < 0.0001). Hunting dogs in Campania region (Southern Italy) are frequently exposed to H. canis, and the infection is potentially associated with close contact with wildlife. Further studies are needed to assess the pathogenic potential of H. canis, as well as the epidemiological relationships between hunting dogs and wild animal populations sharing the same habitats in Southern Italy.
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