ReviewCurrent cardiology reports2020
TAVR in Patients with Pure Aortic Regurgitation: Ready to Use?
Review in Current cardiology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07751965 (Prospective, Multicenter, Single-arm, Open-label Study Evaluating the Safety and Effectiveness of the Myval Transcatheter Heart Valve), which is not on this map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective, Multicenter, Single-arm, Open-label Study Evaluating the Safety and Effectiveness of the Myval Transcatheter Heart Valve (THV) System in High-risk Patients With Severe Symptomatic Non- or Mildly Calcified Aortic Regurgitation.
Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Noncoronary Sinus Pivot Implantation for Transcatheter Aortic Valve Replacement With Self-Expanding Valve for Aortic Regurgitation.JACC. Asia · 2025Article
- Acute aortic regurgitation: a call for urgent intervention.Future cardiology · 2025Article
- MDCT evaluation of dynamic changes in aortic root parameters during the cardiac cycle in patients with aortic regurgitation.Scientific reports · 2025Article
- Transapical Transcatheter Aortic Valve Replacement Under 3-Dimensional Guidance to Treat Pure Aortic Regurgitation in Patients with a Large Aortic Annulus.Reviews in cardiovascular medicine · 2024Article
- Outcome of Transcatheter Aortic Valve Replacement for Pure Native Aortic Regurgitation in Patients with Pulmonary Hypertension.Reviews in cardiovascular medicine · 2024Article
- Aortic valve replacement through right anterior mini-thoracotomy in patients with chronic severe aortic regurgitation: a retrospective single-center study.Journal of Yeungnam medical science · 2024Article
- Review
- Effectiveness and feasibility of transcatheter aortic valve replacement in treating combined aortic and mitral regurgitation: a retrospective observational study.Journal of thoracic disease · 2023Article
- Assessment of valve implantation in the descending aorta as an alternative for aortic regurgitation patients not treatable with conventional procedures.Biomechanics and modeling in mechanobiology · 2023Article
- Predictive model for severe thrombocytopenia after transfemoral transcatheter aortic valve replacement.Frontiers in cardiovascular medicine · 2023Article
- Sutureless aortic valve replacement in pure aortic regurgitation: expanding the indications.Journal of cardiothoracic surgery · 2022Article
- Modified valve-in-valve bailout technique of transcatheter aortic valve replacement in severe aortic regurgitation for valve jumping up to ascending aorta: a case report.European heart journal. Case reports · 2022Article
- Transcatheter Aortic Valve Replacement and Surgical Aortic Valve Replacement Outcomes in Left Ventricular Assist Device Patients with Aortic Insufficiency.Cardiac failure review · 2022Article
- Outcomes of transcatheter aortic valve replacement for pure native aortic regurgitation with the use of newer-Annals of translational medicine · 2022Article
- A case report of ventricular septal defect complicating transcatheter aortic valve implant for aortic regurgitation: novel complication and technical considerations.European heart journal. Case reports · 2021Article
- Challenging Anatomies for TAVR-Bicuspid and Beyond.Frontiers in cardiovascular medicine · 2021Review
- Transcatheter Aortic Valve Replacement in a Patient with Ankylosing Spondylitis and Complex Valvulopathy: Managing Aortic Regurgitation, Mitral Regurgitation, and Ventricular Arrhythmias.Journal of cardiovascular echographyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of the reviewModerate or severe aortic regurgitation (AR) occurs in 0.5% of the population and typically peaks in the fourth to sixth decade of life. A significant proportion of patients have prohibitive surgical risk and are therefore treated medically with pharmacological management of heart failure and no definitive treatment of the underlying valvular pathology. RECENT
findingsTranscatheter aortic valve replacement (TAVR) has been used in an off-label setting to treat AR to attempt to reduce mortality and improve quality of life with varying levels of success. New-generation TAVR devices currently used in AS have demonstrated safety and feasibility when used in patients with AR. Novel TAVR devices dedicated for use in AR are being developed and early studies demonstrate promising results. Ongoing studies with larger clinical trials and novel methods of device anchoring are required, which if positive, will in turn lead to commercial approval and reimbursement, eventually making TAVR ready for use in AR.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.