Evidence map›Paper›PMID 32725284›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2020

Influence of IP-injected ZnO-nanoparticles in Catla catla fish: hematological and serological profile.

Tariq Munir, Muhammad Latif, Arslan Mahmood, Arif Malik, Fahad Shafiq

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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Tariq MunirDepartment of Physics, Government College University Faisalabad (GCUF), Allama Iqbal Road, Faisalabad, 38000, Pakistan. tariqmunir@gcuf.edu.pk.ORCID http://orcid.org/0000-0002-1779-5706
Muhammad LatifDepartment of Zoology, Division of Science and Technology, University of Education Lahore, Lahore, Pakistan. muhammad.lateef@ue.edu.pk.
Arslan MahmoodDepartment of Physics, Government College University Faisalabad (GCUF), Allama Iqbal Road, Faisalabad, 38000, Pakistan.
Arif MalikInstitute of Molecular Biology and Biotechnology (IMBB), University of Lahore, Lahore, Pakistan.
Fahad ShafiqInstitute of Molecular Biology and Biotechnology (IMBB), University of Lahore, Lahore, Pakistan.
Government College University, Faisalabad · PKUniversity of Lahore · PKUniversity of Okara · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study reports an effort to synthesize biocompatible zinc oxide nanoparticles using sol-gel method and its influence on hematological and serological profile of Catla catla fish. Hexagonal wurtzite structure and crystallite size of ZnO-NPs was identified by using XRD in the range of 19 to 20 nm. Moreover, the irregular and non-uniform surface of these NPs was found using SEM. The different stretched and vibrational mode (ZnO, OH, CO, and H-O-H) was identified by using FTIR analysis. UV-visible spectroscopy confirmed absorbance of the blue shift in the range 340 nm. Bioassay of ZnO-NPs on Catla catla was performed and nano ZnO was given through intraperitoneal injections at 0, 25, 50, 75, and 100 μg/g body weight doses. Analysis of fish blood samples indicated an increase in WBCs and leukocytes while the differential effect on monocytes. On the other hand in response to varying ZnO concentrations, an increase in RBCs, hemoglobin, and HCT was evident. Serum analysis revealed an increase in urea concentration while a reduction in creatinine, ALT, and AST. In an overall assessment, nano-ZnO supplementation at 25 to 100 μg/g body weight differentially affected hematological and serum biochemical profile of thaila fish. Graphical abstract.

Indexed as

AnimalsBlood Cell CountDose-Response Relationship, DrugFishesInjections, IntraperitonealMetal NanoparticlesZinc OxideZinc OxideBlood and serum analysisCatla catla fishHexagonal wurtziteZinc oxide nanoparticles

Identifiers

PMID32725284
OpenAlexW3046036372

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.