Evidence map›Paper›PMID 32725271›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Olfactory and taste disorders in healthcare workers with COVID-19 infection.

Ithzel Maria Villarreal, Marta Morato, Mar Martínez-RuizCoello, Andrés Navarro, Raimon Garcia-Chillerón, Álvaro Ruiz, Isabella Vacallanos de Almeida, Luis Mazón, Guillermo Plaza

Open access · bronzeAbstract read
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Parosmia Due to COVID-19 Disease: A 268 Case Series.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  9. Observational
  10. Article
  11. An outlook on coronavirus disease 2019 detection methods.Journal of pharmaceutical analysis · 2022
    Review
  12. Review
  13. Review
  14. Article
  15. Taste loss as a distinct symptom of COVID-19: A systematic review and meta-analysis.medRxiv : the preprint server for health sciences · 2021
    Article
  16. Article
  17. A Review of Neurological Involvement in Patients with SARS-CoV-2 Infection.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Review
  18. Article
  19. Self-reported smell and taste alteration as the sole clinical manifestation of SARS-CoV-2 infection.Oral surgery, oral medicine, oral pathology and oral radiology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ithzel Maria VillarrealENT Department, Hospital Universitario de Fuenlabrada, Universidad Rey Juan Carlos, Camino del Molino, 2, Fuenlabrada, 28942, Madrid, Spain. imvillarrealp@gmail.com.ORCID http://orcid.org/0000-0002-3886-7094
Marta MoratoENT Department, Hospital Universitario de Fuenlabrada, Universidad Rey Juan Carlos, Camino del Molino, 2, Fuenlabrada, 28942, Madrid, Spain.
Mar Martínez-RuizCoelloENT Department, Hospital Universitario de Fuenlabrada, Universidad Rey Juan Carlos, Camino del Molino, 2, Fuenlabrada, 28942, Madrid, Spain.
Andrés NavarroENT Department, Hospital Universitario de Fuenlabrada, Universidad Rey Juan Carlos, Camino del Molino, 2, Fuenlabrada, 28942, Madrid, Spain.
Raimon Garcia-ChillerónENT Department, Hospital Universitario de Fuenlabrada, Universidad Rey Juan Carlos, Camino del Molino, 2, Fuenlabrada, 28942, Madrid, Spain.
Álvaro RuizOccupational Health Department, Hospital Universitario de Fuenlabrada, Madrid, Spain.
Isabella Vacallanos de AlmeidaOccupational Health Department, Hospital Universitario de Fuenlabrada, Madrid, Spain.
Luis MazónOccupational Health Department, Hospital Universitario de Fuenlabrada, Madrid, Spain.
Guillermo PlazaENT Department, Hospital Universitario de Fuenlabrada, Universidad Rey Juan Carlos, Camino del Molino, 2, Fuenlabrada, 28942, Madrid, Spain.
Universidad Rey Juan Carlos · ESHospital Universitario de Fuenlabrada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSevere acute respiratory syndrome caused by COVID-19 has spread globally for the last few months. Healthcare workers (HCW) are overexposed and infection rates are higher than in the rest of the population. Strict clinical assessment is paramount to detect suspicious cases. In this context, olfactory or taste dysfunction (OTD) appears as an early and frequent symptom. Evaluating its presence in early stages plays an important role nowadays.

methodsWe performed a descriptive observational single-center study among 256 HCW at Hospital Universitario de Fuenlabrada affected by COVID-19 and confirmed using RT-PCR. A telephonic interview was performed, after obtaining oral informed consent.

resultsOTD was present in up to 70% of the cases as an early symptom, including mild-to-severe cases. The extent of these sensory deficits lasted an average of 11 days. In 26% of the patients, these sensory alterations persisted for over a month.

conclusionOTD is reported as an early symptom among HCW with SARS-CoV-2 infection. Its strong association with test positivity is useful in the management of the infection and should be enough to indicate preventive isolation. We consider that OTD needs to be included in clinical screening questionnaires in HCW.

Indexed as

COVID-19Olfaction DisordersHealth PersonnelHumansSARS-CoV-2SmellTaste DisordersAgeusiaAnosmiaCOVID-19Healthcare workersOlfactory and taste disorders

Identifiers

PMID32725271
PMCPMC7385204
OpenAlexW3045563852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.