Evidence map›Paper›PMID 32725235›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020

Decision Making and Implementation of the First Public Sector Introduction of Typhoid Conjugate Vaccine-Navi Mumbai, India, 2018.

Kashmira Date, Rahul Shimpi, Stephen Luby, Ramaswami N, Pradeep Haldar, Arun Katkar, Kathleen Wannemuehler, Vittal Mogasale, Sarah Pallas, Dayoung Song and 10 more

Open access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Programmatic Effectiveness of a Pediatric Typhoid Conjugate Vaccine Campaign in Navi Mumbai, India.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
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  8. IAPSM's Position Paper on Typhoid Vaccines for Adult Immunization in India.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 3 countries.

Kashmira DateGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Rahul ShimpiWorld Health Organization, India Country Office, New Delhi, India.
Stephen LubyStanford University, Stanford, California, USA.
Ramaswami NNavi Mumbai Municipal Corporation, Navi Mumbai, India.
Pradeep HaldarMinistry of Health and Family Welfare, Government of India, India.
Arun KatkarWorld Health Organization, India Country Office, New Delhi, India.
Kathleen WannemuehlerGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Vittal MogasaleInternational Vaccine Institute, Republic of Korea.
Sarah PallasGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Dayoung SongInternational Vaccine Institute, Republic of Korea.
Abhishek KunwarWorld Health Organization, India Country Office, New Delhi, India.
Anagha LoharikarGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Vijay YewaleDr. Yewale Multispecialty Hospital, Navi Mumbai, India.
Danish AhmedWorld Health Organization, India Country Office, New Delhi, India.
Lily HorngStanford University, Stanford, California, USA.
Elisabeth WilhelmGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Sunil BahlWorld Health Organization, Regional Office for South-East Asia, New Delhi, India.
Pauline HarveyWorld Health Organization, India Country Office, New Delhi, India.
Shanta DuttaNational Institute of Cholera and Enteric Diseases-Indian Council for Medical Research, Kolkata, India.
Pankaj BhatnagarWorld Health Organization, India Country Office, New Delhi, India.
World Health Organization - India · INCenters for Disease Control and Prevention · USInternational Vaccine Institute · KRStanford University · USAxis Multispecialty Hospital · INBrihanmumbai Municipal Corporation · INGovernment of India · INNational Institute of Cholera and Enteric Diseases · INWorld Health Organization Regional Office for South-East Asia · IN

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundTyphoid fever prevention and control efforts are critical in an era of rising antimicrobial resistance among typhoid pathogens. India remains one of the highest typhoid disease burden countries, although a highly efficacious typhoid conjugate vaccine (TCV), prequalified by the World Health Organization in 2017, has been available since 2013. In 2018, the Navi Mumbai Municipal Corporation (NMMC) introduced TCV into its immunization program, targeting children aged 9 months to 14 years in 11 of 22 areas (Phase 1 campaign). We describe the decision making, implementation, and delivery costing to inform TCV use in other settings.

methodsWe collected information on the decision making and campaign implementation in addition to administrative coverage from NMMC and partners. We then used a microcosting approach from the local government (NMMC) perspective, using a new Microsoft Excel-based tool to estimate the financial and economic vaccination campaign costs.

resultsThe planning and implementation of the campaign were led by NMMC with support from multiple partners. A fixed-post campaign was conducted during weekends and public holidays in July-August 2018 which achieved an administrative vaccination coverage of 71% (ranging from 46% in high-income to 92% in low-income areas). Not including vaccine and vaccination supplies, the average financial cost and economic cost per dose of TCV delivery were $0.45 and $1.42, respectively.

conclusionThe first public sector TCV campaign was successfully implemented by NMMC, with high administrative coverage in slums and low-income areas. Delivery cost estimates provide important inputs to evaluate the cost-effectiveness and affordability of TCV vaccination through public sector preventive campaigns.

Indexed as

Typhoid FeverTyphoid-Paratyphoid VaccinesChildDecision MakingHumansImmunization ProgramsIndiaPublic SectorVaccinationVaccines, ConjugateTyphoid-Paratyphoid VaccinesVaccines, ConjugateSalmonella Typhityphoidtyphoid conjugate vaccinevaccine introduction

Identifiers

PMID32725235
PMCPMC7420725
OpenAlexW3046256277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.