Evidence map›Paper›PMID 32724465›Full record

ArticleTheranostics2020

Dissolving Microneedles with Spatiotemporally controlled pulsatile release Nanosystem for Synergistic Chemo-photothermal Therapy of Melanoma.

Wanbing Qin, Guilan Quan, Ying Sun, Minglong Chen, Peipei Yang, Disang Feng, Ting Wen, Xinyu Hu, Xin Pan, Chuanbin Wu

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.

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  19. BiomineralizedTheranostics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Wanbing QinSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Guilan QuanCollege of Pharmacy, Jinan University, Guangzhou, 510632, China.
Ying SunSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Minglong ChenSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Peipei YangDepartment of Pharmacy, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China.
Disang FengCollege of Pharmacy, Jinan University, Guangzhou, 510632, China.
Ting WenSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Xinyu HuSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Xin PanSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Chuanbin WuSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Sun Yat-sen University · CNJinan University · CNGuangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High aggressiveness and recurrence of melanoma tumors require multiple systemic drug administrations, causing discomfort and severe side effects to the patients. Topical treatment strategies that provide repetitively controllable and precise drug administrations will greatly improve treatment effects.

Indexed as

AnimalsCell Line, TumorCombined Modality TherapyDrug CompoundingDrug Delivery SystemsDrug LiberationFemaleHumansIndolesLasersLightMelanoma, ExperimentalMiceNanoparticlesPaclitaxelPhotosensitizing Agents2-(2-(2-chloro-3-((1,3-dihydro-3,3-dimethyl-1-propyl-2H-indol-2-ylidene)ethylidene)-1-cyclohexen-1-yl)ethenyl)-3,3-dimethyl-1-propylindoliumIndolesPaclitaxelPhotosensitizing Agentschemo-photothermal therapydissolving microneedlesmelanomasolid lipid nanoparticlestriggered release

Identifiers

PMID32724465
PMCPMC7381723
OpenAlexW3045425668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.