Evidence map›Paper›PMID 32724421›Full record

ArticleOncology letters2020

Effects of the IL6 -174G>C promoter polymorphism and IL-6 serum levels on the progression of cutaneous malignant melanoma.

Tatyana Vlaykova, Mateuzh Kurzawski, Tanya Tacheva, Dimo Dimov, Asen Anastasov, Denitsa Vlaykova, Ani Miteva, Niamh O'donoghue, Marek Drozdzik

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Tatyana VlaykovaDepartment of Chemistry and Biochemistry, Medical Faculty, Trakia University, Stara Zagora 6000, Bulgaria.
Mateuzh KurzawskiDepartment of Experimental and Clinical Pharmacology, Pomeranian Medical University, Szczecin 70-204, Poland.
Tanya TachevaDepartment of Chemistry and Biochemistry, Medical Faculty, Trakia University, Stara Zagora 6000, Bulgaria.
Dimo DimovDepartment of Chemistry and Biochemistry, Medical Faculty, Trakia University, Stara Zagora 6000, Bulgaria.
Asen AnastasovDepartment of Chemistry and Biochemistry, Medical Faculty, Trakia University, Stara Zagora 6000, Bulgaria.
Denitsa VlaykovaDepartment of Chemistry and Biochemistry, Medical Faculty, Trakia University, Stara Zagora 6000, Bulgaria.
Ani MitevaDepartment of Medical Ethics and Law, Faculty of Public Health, Medical University of Sofia, Sofia 1431, Bulgaria.
Niamh O'donoghueDepartment of Chemistry and Biochemistry, Medical Faculty, Trakia University, Stara Zagora 6000, Bulgaria.
Marek DrozdzikDepartment of Experimental and Clinical Pharmacology, Pomeranian Medical University, Szczecin 70-204, Poland.
Trakia University · BGPomeranian Medical University · PLMedical University of Sofia · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous malignant melanoma (CMM) is one of the most immunogenic types of cancer, with a 6-fold higher rate of spontaneous regression than any other malignancy. In addition to responsiveness to different immunotherapies, the immunogenicity of CMM highlights the important role of the host immune system in the response to CMM. The present study aimed to explore the role of two functional promoter polymorphisms [

Indexed as

cytokinesinterleukin-6melanomapolymorphismtumor necrosis factor-α

Identifiers

PMID32724421
PMCPMC7377025
OpenAlexW3035581193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.