Evidence map›Paper›PMID 32724416›Full record

ArticleOncology letters2020

Increased expression of EHMT2 associated with H3K9me2 level contributes to the poor prognosis of gastric cancer.

Ping Chen, Qi Qian, Zhiyuan Zhu, Xiaohui Shen, Shenling Yu, Zhenghong Yu, Rui Sun, Yiping Li, Didi Guo, Hong Fan

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ping ChenDepartment of Oncology, Yancheng First People's Hospital, Yancheng, Jiangsu 224005, P.R. China.
Qi QianDepartment of Oncology, Yancheng First People's Hospital, Yancheng, Jiangsu 224005, P.R. China.
Zhiyuan ZhuDepartment of Oncology, Yancheng First People's Hospital, Yancheng, Jiangsu 224005, P.R. China.
Xiaohui ShenDepartment of Medical Genetics and Developmental Biology, Medical School of Southeast University, Nanjing, Jiangsu 210009, P.R. China.
Shenling YuDepartment of Medical Genetics and Developmental Biology, Medical School of Southeast University, Nanjing, Jiangsu 210009, P.R. China.
Zhenghong YuDepartment of Medical Oncology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, P.R. China.
Rui SunDepartment of Pathology, Medical School of Southeast University, Nanjing, Jiangsu 210009, P.R. China.
Yiping LiDepartment of Pathology, Medical School of Southeast University, Nanjing, Jiangsu 210009, P.R. China.
Didi GuoDepartment of Medical Genetics and Developmental Biology, Medical School of Southeast University, Nanjing, Jiangsu 210009, P.R. China.
Hong FanDepartment of Medical Genetics and Developmental Biology, Medical School of Southeast University, Nanjing, Jiangsu 210009, P.R. China.
Southeast University · CNNantong University · CNNanjing Medical University · CNYancheng First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Di-methylated lysine 9 of histone H3 (H3K9me2), regulated by histone methyltransferases, is involved in the epigenetic regulation of tumor-associated genes. The present study aimed to evaluate whether the H3K9me2 methylation level is associated with the expression level of euchromatic histone lysine methyltransferase 2 (EHMT2) in the prognosis of gastric cancer (GC). H3K9me2 methylation level and EHMT2 expression level were detected by immunohistochemistry in 118 GC samples. The clinicopathological significance of H3K9me2 and EHMT2 in patients with GC was assessed using a paired Student's t-test, χ

Indexed as

chromatin remodelingdi-methylated lysine 9 of histone H3euchromatic histone lysine methyltransferase 2gastric cancerhistone methylation

Identifiers

PMID32724416
PMCPMC7377055
OpenAlexW3033491362

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.