Evidence map›Paper›PMID 32724321›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Effectiveness and Safety of

Lei Shen, Si Ra Gwak, Jong Cheon Joo, Bong Keun Song, Seon Woo Cha, Young Uk Song, Mi Kyung Pyo, Soo Jung Park

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Lei ShenDepartment of Constitutional Medicine, College of Korean Medicine, Wonkwang University, Iksan 54538, Republic of Korea.
Si Ra GwakDepartment of Constitutional Medicine, College of Korean Medicine, Wonkwang University, Iksan 54538, Republic of Korea.
Jong Cheon JooDepartment of Constitutional Medicine, College of Korean Medicine, Wonkwang University, Iksan 54538, Republic of Korea.
Bong Keun SongDepartment of Internal Medicine, College of Korean Medicine, Wonkwang University, Gwangju 51729, Republic of Korea.
Seon Woo ChaInternational Ginseng and Herb Research Institute, Geumsan 32724, Republic of Korea.
Young Uk SongDaedong Korea Ginseng Co., Ltd., Geumsan 32718, Republic of Korea.
Mi Kyung PyoInternational Ginseng and Herb Research Institute, Geumsan 32724, Republic of Korea.ORCID https://orcid.org/0000-0001-9229-3282
Soo Jung ParkDepartment of Sasang Constitutional Medicine, College of Korean Medicine, Woosuk University, Jeonju 55338, Republic of Korea.ORCID https://orcid.org/0000-0001-8191-4290
Wonkwang University · KRInternational Ginseng & Herb Research Institute · KRKorean Society of Ginseng · KRWoosuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to evaluate the efficacy and safety of

methodsA randomized, double-blind, placebo-controlled clinical trial was conducted from December 2017 to January 2019. The trial included 60 subjects between the ages of 19 and 70 who had higher alanine transaminase (ALT) levels than the normal upper limit. The subjects were randomly divided into two groups: GS-KG9 (

resultsOut of 60 subjects, nine were excluded from the efficacy analysis because they met the exclusion criteria. Therefore, a total of 51 subjects were evaluated for the effectiveness of the treatment (26 in the GS-KG9 group and 25 in the placebo group). After 12 weeks of treatment, the ALT levels were significantly reduced in the GS-KG9 group compared to the placebo group (

conclusionThe results of this trial suggest that GS-KG9 might be an effective and safe option for mild hepatic dysfunction. This trial is registered with KCT0004080.

Identifiers

PMID32724321
PMCPMC7381953
OpenAlexW3042763115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.