ArticleIndian journal of anaesthesia2020
Is an opioid-free anaesthesia possible without using alpha-2 agonists?
Article in Indian journal of anaesthesia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 8 citations in OpenAlex.
- Preemptive low-dose intravenous ketamine in the management of acute and chronic postoperative pain following laparoscopic cholecystectomy: a prospective randomized control study.Medical gas researchTrial
- Esketamine/dexmedetomidine-based opioid-free anesthesia and its association with postoperative bowel and cognitive dysfunction after total laparoscopic hysterectomy.BMC anesthesiology · 2025Observational
- Pain Management Following Intracavitary Brachytherapy Procedures: A Prospective, Randomized, Double-Blind Study.Cureus · 2024Article
- Efficacy of intravenous dexmedetomidine-lignocaine infusion compared to morphine for intraoperative haemodynamic stability in modified radical mastectomy: A randomised controlled trial.Indian journal of anaesthesia · 2023Article
- Opioid-free anaesthesia: The conundrum and the solutions.Indian journal of anaesthesia · 2022Article
- Effect of intraoperative intravenous lignocaine infusion on the haemodynamic stability and postoperative recovery following intracranial aneurysm surgery: A case series.Indian journal of anaesthesia · 2020Article
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
Opioid-free anaesthesia (OFA) is an anaesthetic technique where non-opioid drugs are used in the intraoperative period. It can be successful without using alpha-2 agonists, which are main drugs used in this multimodal anaesthesia. We are presenting seven different cases where OFA was used in different abdominal surgeries (laparoscopic cholecystectomy, colon cancer operation, and laparoscopic inguinal hernia repair) alone or in a combination with epidural anaesthesia and peripheral nerve block. Prior induction to general anaesthesia all patients received dexamethasone and paracetamol. Induction of general anaesthesia consisted of giving midazolam, lignocaine, propofol, ketamine, and rocuronium. After tracheal intubation anaesthesia was maintained with sevoflurane and continuous infusion with lignocaine, magnesium sulphate, and ketamine (in some patients). At the end of the surgery, all patients received metamizole. The postoperative pain scores were reduced in most of the patients without giving opioids.
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