ArticleIndian journal of anaesthesia2020
Effect of intravenous lignocaine infusion on bispectral index during spinal anaesthesia for caesarean section: A prospective randomised double-blind study.
Article in Indian journal of anaesthesia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04741880 (Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia With Isobaric Bupivacaine in Patients Undergoing Surgery to Treat Skin and Soft Tissue Tumors of the Lower Limbs), which is not on this map. Cited by 5 papers.
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Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia With Isobaric Bupivacaine in Patients Undergoing Surgery to Treat Skin and Soft Tissue Tumors of the Lower Limbs
Who cites it
5 citing papers in PubMed.
- The effect of intravenous lidocaine infusion on subarachnoid anesthesia in patients undergoing total knee replacement: a randomised controlled trial.Journal of anesthesia · 2025Trial
- Opioid-free anaesthesia for laparoscopic surgeries - A prospective non-randomised study in a tertiary care hospital.Indian journal of anaesthesia · 2022Article
- Effect of intraoperative intravenous lignocaine infusion on the haemodynamic stability and postoperative recovery following intracranial aneurysm surgery: A case series.Indian journal of anaesthesia · 2020Article
- Perioperative intravenous lidocaine: Crossing local boundaries and reaching systemic horizons.Indian journal of anaesthesia · 2020Article
- Intra-arterial regional anesthesia for pain associated with arteriovenous malformations sclerotherapy.Journal of anaesthesiology, clinical pharmacologyArticle
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4 authors.
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Abstract
BACKGROUND AND
aimsSystemic lignocaine has been shown to have sedative effects. We designed this randomised-double-blind, placebo-controlled study to evaluate the effect of intravenous lignocaine on the bispectral index (BIS) during caesarean section under spinal anaesthesia.
methods80 patients scheduled for elective caesarean section under spinal anaesthesia were randomly allocated to 2 study groups. Group L received intravenous 1.5 mg/kg of lignocaine bolus, 15 minutes before spinal anaesthesia followed by an intravenous infusion 1.5 mg/kg/h for 60 minutes intravenously. The patients in the control group (C group) were given 0.9% sodium chloride in a double-blind fashion. Spinal anaesthesia was performed with 10 mg of 0.5% bupivacaine. The changes of Sao2, BIS and hemodynamic variables during caesarean section, Apgar score of neonate and the incidence of adverse effects were recorded.
resultsBIS values were lower in the L group compared to C group (
conclusionIntravenous lignocaine infusion given with spinal anaesthesia in women undergoing elective caesarean delivery providing lower BIS values without respiratory depression, in the absence of foetal compromise.
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