ArticleThe ISME journal2020
A spore quality-quantity tradeoff favors diverse sporulation strategies in Bacillus subtilis.
Article in The ISME journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 48 citations in OpenAlex.
- Distinctive spore architecture and developmental biology ofJournal of bacteriology · 2026Article
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- Transcriptomics and Metabolomics Reveal the Antagonistic Mechanism ofMicroorganisms · 2026Article
- Sporicidal and Anti-germinative Effects of Achyrocline satureioides Extract on Paenibacillus larvae: A Potential Natural Strategy for American Foulbrood Control.Current microbiology · 2026Article
- Evolutionary bioenergetics of sporulation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Contribution of theMicrobiology spectrum · 2026Article
- Bottleneck size drives the evolution of cooperative traits in an aggregative multicellular myxobacterium.PLoS biology · 2026Article
- Real-time nanoscale investigation of spore coat assembly in Bacillus subtilis.Communications biology · 2025Article
- Phosphorelay changes and plasticity underlie the life history evolution ofMicrobiology (Reading, England) · 2025Article
- Bacillus subtilis ensures high spore quality in competition with Salmonella Typhimurium via the SigB-dependent pathway.The ISME journal · 2025Article
- Pan-genome-scale metabolic modeling ofmSystems · 2024Article
- A cross-systems primer for synthetic microbial communities.Nature microbiology · 2024Review
- The megaplasmid pCER270 ofApplied and environmental microbiology · 2024Article
- Translation in Bacillus subtilis is spatially and temporally coordinated during sporulation.Nature communications · 2024Article
- Trade-offs, trade-ups, and high mutational parallelism underlie microbial adaptation during extreme cycles of feast and famine.Current biology : CB · 2024Article
- Clostridioides difficile Sporulation.Advances in experimental medicine and biology · 2024Review
- Attempts to limit sporulation in the probiotic strainAccess microbiology · 2023Article
- Glutamate catabolism during sporulation determines the success of the future spore germination.iScience · 2022Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quality-quantity tradeoffs govern the production of propagules across taxa and can explain variability in life-history traits in higher organisms. A quality-quantity tradeoff was recently discovered in spore forming bacteria, but whether it impacts fitness is unclear. Here we show both theoretically and experimentally that the nutrient supply during spore revival determines the fitness advantage associated with different sporulation behaviors in Bacillus subtilis. By tuning sporulation rates we generate spore-yield and spore-quality strategists that compete with each other in a microscopic life-cycle assay. The quality (yield) strategist is favored when spore revival is triggered by poor (rich) nutrients. We also show that natural isolates from the gut and soil employ different life-cycle strategies that result from genomic variations in the number of rap-phr signaling systems. Taken together, our results suggest that a spore quality-quantity tradeoff contributes to the evolutionary adaptation of sporulating bacteria.
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