Evidence map›Paper›PMID 32724083›Full record

ArticleNature communications2020

Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments.

Anett Jandke, Daisy Melandri, Leticia Monin, Dmitry S Ushakov, Adam G Laing, Pierre Vantourout, Philip East, Takeshi Nitta, Tomoya Narita, Hiroshi Takayanagi and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
  2. γδ T cells in colorectal and liver cancer.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  3. A Genome-Wide Association Study of Takotsubo Syndrome.JACC. Basic to translational science · 2026
    Article
  4. Article
  5. International journal of molecular sciences · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Cancer immunotherapy by γδ T cells.Science (New York, N.Y.) · 2024
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anett JandkeImmunosurveillance Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW11AT, UK.ORCID http://orcid.org/0000-0002-7681-7952
Daisy MelandriImmunosurveillance Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW11AT, UK.ORCID http://orcid.org/0000-0002-8022-2345
Leticia MoninImmunosurveillance Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW11AT, UK.ORCID http://orcid.org/0000-0002-4951-8105
Dmitry S UshakovImmunosurveillance Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW11AT, UK.ORCID http://orcid.org/0000-0001-7109-4217
Adam G LaingImmunosurveillance Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW11AT, UK.
Pierre VantouroutImmunosurveillance Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW11AT, UK.ORCID http://orcid.org/0000-0001-7287-5517
Philip EastBioinformatics and Biostatistics Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW11AT, UK.
Takeshi NittaDepartment of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-0033, Japan.ORCID http://orcid.org/0000-0003-2384-3062
Tomoya NaritaDepartment of Pharmacotherapy, Research Institute of Pharmaceutical Sciences, Musashino University, Nishitokyo, Tokyo, 202-8585, Japan.
Hiroshi TakayanagiDepartment of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-0033, Japan.
Regina FeederleMonoclonal Antibody Core Facility, Institute for Diabetes and Obesity, Helmholtz Zentrum, München, German Research Centre for Environmental Health, 85764, Neuherberg, Germany.ORCID http://orcid.org/0000-0002-3981-367X
Adrian HaydayImmunosurveillance Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW11AT, UK. Adrian.hayday@crick.ac.uk.ORCID http://orcid.org/0000-0002-9495-5793

Funding

Cancer Research UK FC001093Medical Research Council FC001093Wellcome Trust 106292/Z/14/ZWellcome Trust FC001093
6 · The paper itself

Abstract

Butyrophilin-like (Btnl) genes are emerging as major epithelial determinants of tissue-associated γδ T cell compartments. Thus, the development of signature, murine TCRγδ

Indexed as

Immunity, CellularAnimalsButyrophilinsGene Expression ProfilingIntestinal MucosaIntraepithelial LymphocytesMiceMice, TransgenicReceptors, Antigen, T-Cell, gamma-deltaButyrophilinsReceptors, Antigen, T-Cell, gamma-delta

Identifiers

PMID32724083
PMCPMC7387338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.