ArticleNature communications2020
Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
60 citing papers in PubMed.
- Motivation to exert effort dynamically adapts to reward context and environmental controllability.Cognitive, affective & behavioral neuroscience · 2026Article
- Article
- Ultrasound neuromodulation reveals distinct roles of the dorsal anterior cingulate cortex and anterior insula in learning.PLoS biology · 2026Article
- Comparing the Limbic-Frontal Connectome across the Primate Order: Conservation of Connections and Implications for Translational Neuroscience.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Cell-type-specific sustained value representations in the claustrum.bioRxiv : the preprint server for biology · 2026Article
- Activity in human dorsal raphe nucleus signals changes in behavioural policy.Nature communications · 2026Article
- Humans are more prosocial in poor foraging environments.Nature communications · 2026Article
- Uncertainty and reward histories have distinct effects on decisions after wins and losses.Scientific reports · 2026Article
- Interaction and functional specialization across a distributed neural circuit for flexible task control in macaques.Nature communications · 2026Article
- A computational mechanism linking momentary craving and decision-making in alcohol drinkers and cannabis users.Nature. Mental health · 2026Article
- Active disambiguation guides inferring controllability and cause in social interactions.Nature communications · 2025Article
- Epigenetic manipulation of anterior insular cortex alters neural signals and cognitive control.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Psychological interventions that decrease psychological distance or challenge system justification increase motivation to exert effort to mitigate climate change.Communications psychology · 2025Article
- Neurocomputational basis of learning when choices simultaneously affect both oneself and others.Nature communications · 2025Article
- Fundamental features of social environments determine rate of social affiliation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- An Information-Theoretic Framework for Understanding Learning and Choice Under Uncertainty.Entropy (Basel, Switzerland) · 2025Article
- Ventromedial prefrontal cortex lesions disrupt learning to reward others.Brain : a journal of neurology · 2025Article
- Dorsal raphe nucleus controls motivation-state transitions in monkeys.Science advances · 2025Article
- Stochastic decisions support optimal foraging of volatile environments, and are disrupted by anxiety.Cognitive, affective & behavioral neuroscience · 2025Article
- Stimulus uncertainty and relative reward rates determine adaptive responding in perceptual decision-making.PLoS computational biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
People and other animals learn the values of choices by observing the contingencies between them and their outcomes. However, decisions are not guided by choice-linked reward associations alone; macaques also maintain a memory of the general, average reward rate - the global reward state - in an environment. Remarkably, global reward state affects the way that each choice outcome is valued and influences future decisions so that the impact of both choice success and failure is different in rich and poor environments. Successful choices are more likely to be repeated but this is especially the case in rich environments. Unsuccessful choices are more likely to be abandoned but this is especially likely in poor environments. Functional magnetic resonance imaging (fMRI) revealed two distinct patterns of activity, one in anterior insula and one in the dorsal raphe nucleus, that track global reward state as well as specific outcome events.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.