Evidence map›Paper›PMID 32723920›Full record

ArticlemBio2020

FEDS: a Novel Fluorescence-Based High-Throughput Method for Measuring DNA Supercoiling

Alexandre Duprey, Eduardo A Groisman

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The regulation of DNA supercoiling across evolution.Protein science : a publication of the Protein Society · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Alexandre DupreyDepartment of Microbial Pathogenesis, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-8310-8508
Eduardo A GroismanDepartment of Microbial Pathogenesis, Yale School of Medicine, New Haven, Connecticut, USA eduardo.groisman@yale.edu.ORCID 0000-0001-6860-7691

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Expanding the SensingAbilities of Virulence Regulatory SystemsR01AI120558 · NIAID · YALE UNIVERSITY · PI GROISMAN, EDUARDO · 2016 to 2019
$2.2M
Elucidating the Sensing Abilities of Virulence Regulatory SystemsR56AI120558 · NIAID · YALE UNIVERSITY · PI GROISMAN, EDUARDO · 2021 to 2021
$540k
NCATS NIH HHS UL1 TR001863NIAID NIH HHS R01 AI120558NIAID NIH HHS R56 AI120558
6 · The paper itself

Abstract

DNA supercoiling (DS) is essential for life because it controls critical processes, including transcription, replication, and recombination. Current methods to measure DNA supercoiling

Indexed as

FluorescenceDNA, BacterialDNA, SuperhelicalEscherichia coliGene Expression Regulation, BacterialHigh-Throughput Screening AssaysPlasmidsSalmonella entericaTranscription, GeneticDNA, BacterialDNA, SuperhelicalDNA gyraseDNA topologyfeedback loopgene transcription

Identifiers

PMID32723920
PMCPMC7387798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.