ArticlemBio2020
Interactions of Monocytes, HIV, and ART Identified by an Innovative scRNAseq Pipeline: Pathways to Reservoirs and HIV-Associated Comorbidities.
Open access · goldAbstract read
In one paragraph
Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
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Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
- Dynamic changes of monocytes-related immune activation in people with HIV switching to long-acting injectable cabotegravir plus rilpivirine.Scientific reports · 2026Article
- Neuroinflammatory crosstalk between microglia and astrocytes increases viral replication in an iPSC-derived model of CNS HIV infection.Scientific reports · 2026Article
- Astragalus polysaccharide promotes latent HIV-1 reactivation via exosome-mediated modulation of the PI3K/AKT/NF-κB axis.Extracellular vesicles and circulating nucleic acids · 2026Article
- Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia.Nature communications · 2025Article
- Neuroinflammatory crosstalk between microglia and astrocytes increases viral replication in an iPSC-derived model of CNS HIV infection.bioRxiv : the preprint server for biology · 2025Article
- Advances in Single-Cell Sequencing for Infectious Diseases: Progress and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Tracking HIV persistence across T cell lineages during early ART-treated HIV-1-infection using a reservoir-marking humanized mouse model.Nature communications · 2025Article
- Monocytes across life span in HIV infection: lights and shadows.Current opinion in HIV and AIDS · 2025Review
- Single-cell analysis of CD14Frontiers in immunology · 2025Article
- Cerebrospinal Fluid and Peripheral Blood Lymphomonocyte Single-Cell Transcriptomics in a Subject with Multiple Sclerosis Acutely Infected with HIV.International journal of molecular sciences · 2024Article
- Toll-Like Receptor Genes and Risk of Latent Tuberculosis Infection in People Infected with HIV-1.Viruses · 2024Article
- HIV-1 infection of genetically engineered iPSC-derived central nervous system-engrafted microglia in a humanized mouse model.Journal of virology · 2023Article
- Single-Cell Transcriptomics ofCells · 2023Review
- HIV-1 activates oxidative phosphorylation in infected CD4 T cells in a human tonsil explant model.Frontiers in immunology · 2023Article
- Venus: An efficient virus infection detection and fusion site discovery method using single-cell and bulk RNA-seq data.PLoS computational biology · 2022Article
- Methamphetamine Dysregulates Macrophage Functions and Autophagy to Mediate HIV Neuropathogenesis.Biomedicines · 2022Article
- Buprenorphine reverses neurocognitive impairment in EcoHIV infected mice: A potential therapy for HIV-NCI.Frontiers in immunology · 2022Article
- Methamphetamine induces transcriptional changes in cultured HIV-infected mature monocytes that may contribute to HIV neuropathogenesis.Frontiers in immunology · 2022Article
- Article
- Cryopreservation of microglia enables single-cell RNA sequencing with minimal effects on disease-related gene expression patterns.iScience · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Rosiris León-RiveraDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0002-3517-2481
Brenda MorseyDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Meng NiuDepartment of Genetics, Cell Biology & Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Howard S Fox *Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Joan W Berman *Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA joan.berman@einsteinmed.org.ORCID 0000-0003-0635-4072
University of Nebraska Medical Center · USAlbert Einstein College of Medicine · US
Funding
UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI PAUL L SORGEN · 2012 to 2026
$59.2MUNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Joann B. Sweasy · 1985 to 2026
$55.0MTherapeutics Core (Page 286)P30MH062261 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BUCH, SHILPA J., FOX, HOWARD S · 2000 to 2021
$37.7MMEDICAL SCIENTIST TRAINING PROGRAMT32GM007288 · NIGMS · YESHIVA UNIVERSITY · PI AKABAS, MYLES H. · 1985 to 2022
$35.6MPatient and Population Health Outcomes Research SWGP30AI124414 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Kathryn M. Anastos · 2017 to 2026
$28.3MUNMC Histology/Imaging and Creighton University Imaging Core FacilityP30GM110768 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WALSH, EDWARD J · 2014 to 2018
$5.1MMechanisms of opioid- mediated HIV neuropathogenesisR01DA048609 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI BERMAN, JOAN WEINBERGER, GOLDSTEIN, HARRIS · 2019 to 2023
$4.2MImpact of illicit drugs, HIV, and ART on neuroinflammation and BBB disruptionR01DA044584 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BERMAN, JOAN WEINBERGER, GOLDSTEIN, HARRIS · 2017 to 2021
$4.0MThe brain as a SIV reservoir under suppressive cART potentiation by drugs of abuseR01DA043164 · NIDA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BUCH, SHILPA J., BYRAREDDY, SIDDAPPA N · 2016 to 2020
$3.8MMonocyte CNS HIV entry & neurodegeneration: Translational studies in the CART eraR01MH112391 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BERMAN, JOAN WEINBERGER, MORGELLO, SUSAN · 2017 to 2021
$3.7MMolecular Mechanisms of Increased Risk of Racial and Ethnic Minorities for HIV Associated Neurocognitive DisordersF31MH116825 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI LEON RIVERA, ROSIRIS · 2018 to 2020
$150kNCI NIH HHS P30 CA036727NIAID NIH HHS P30 AI124414NIDA NIH HHS R01 DA043164NIDA NIH HHS R01 DA044584NIDA NIH HHS R01 DA048609NIGMS NIH HHS P20 GM103427NIGMS NIH HHS P30 GM110768NIGMS NIH HHS T32 GM007288NIMH NIH HHS F31 MH116825NIMH NIH HHS P30 MH062261NIMH NIH HHS R01 MH112391
Abstract
HIV reservoirs persist despite successful antiretroviral therapy (ART) and are a major obstacle to the eradication and cure of HIV. The mature monocyte subset, CD14
Indexed as
Anti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveCells, CulturedDisease ReservoirsHIVHumansMonocytesSequence Analysis, RNASingle-Cell AnalysisAnti-Retroviral AgentsHIVHIV-associated comorbiditieslatencyreservoirstranscriptome
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.