Evidence map›Paper›PMID 32723820›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Selective translation by alternative bacterial ribosomes.

Yu-Xiang Chen, Zhi-Yu Xu, Xueliang Ge, Suparna Sanyal, Zhi John Lu, Babak Javid

Erratum issuedAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Ribosome hibernation in zinc-starvedMicrobiology spectrum · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. AACS infectious diseases · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Yu-Xiang ChenCentre for Global Health and Infectious Diseases, Collaborative Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, Tsinghua University School of Medicine, 100084 Beijing, China.
Zhi-Yu XuCentre for Global Health and Infectious Diseases, Collaborative Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, Tsinghua University School of Medicine, 100084 Beijing, China.
Xueliang GeDepartment of Cell and Molecular Biology, Uppsala University, 75124 Uppsala, Sweden.ORCID 0000-0001-7954-3195
Suparna SanyalDepartment of Cell and Molecular Biology, Uppsala University, 75124 Uppsala, Sweden.ORCID 0000-0002-7124-792X
Zhi John LuMinistry of Education Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, 100084 Beijing, China; zhilu@tsinghua.edu.cn bjavid@gmail.com.
Babak JavidCentre for Global Health and Infectious Diseases, Collaborative Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, Tsinghua University School of Medicine, 100084 Beijing, China; zhilu@tsinghua.edu.cn bjavid@gmail.com.ORCID 0000-0002-6354-6305

Funding

Wellcome TrustWellcome Trust 207487/C/17/Z
6 · The paper itself

Abstract

Alternative ribosome subunit proteins are prevalent in the genomes of diverse bacterial species, but their functional significance is controversial. Attempts to study microbial ribosomal heterogeneity have mostly relied on comparing wild-type strains with mutants in which subunits have been deleted, but this approach does not allow direct comparison of alternate ribosome isoforms isolated from identical cellular contexts. Here, by simultaneously purifying canonical and alternative RpsR ribosomes from

Indexed as

Bacterial ProteinsIronMycobacterium smegmatisPeptide Chain Initiation, TranslationalProtein BiosynthesisRibosomal ProteinsRibosomesRibosome SubunitsBacterial ProteinsIronRibosomal Proteinsribosomal protein S18alternative ribosomesmycobacteriumribosome profiling

Identifiers

PMID32723820
PMCPMC7431078

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.