Evidence map›Paper›PMID 32723789›Full record

ArticlemSystems2020

Consumption of a Western-Style Diet Modulates the Response of the Murine Gut Microbiome to Ciprofloxacin.

Damien J Cabral, Jenna I Wurster, Benjamin J Korry, Swathi Penumutchu, Peter Belenky

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 37 citations in OpenAlex.

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  13. Antibiotic perturbations to the gut microbiome.Nature reviews. Microbiology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Damien J Cabral *Department of Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island, USA.
Jenna I Wurster *Department of Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island, USA.
Benjamin J KorryDepartment of Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island, USA.
Swathi PenumutchuDepartment of Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island, USA.
Peter BelenkyDepartment of Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island, USA peter_belenky@brown.edu.ORCID https://orcid.org/0000-0002-1682-945X
Brown University · US

Funding

The role of Sirtuins in neurodegenerative diseaseP20GM109035 · NIGMS · BROWN UNIVERSITY · PI WONG, IAN Y · 2016 to 2025
$22.6M
Using Genomic Epidemiology to Identify Transmission Patterns and Inform Intervention Strategies for Antibiotic-Resistant N. GonorrhoeaeP20GM121344 · NIGMS · MIRIAM HOSPITAL · PI D'AGATA, ERIKA M · 2018 to 2022
$9.4M
Predoctoral Training Program in Biological Data Science at Brown UniversityT32GM128596 · NIGMS · BROWN UNIVERSITY · PI RAMACHANDRAN, SOHINI, SANDSTEDE, BJORN · 2018 to 2022
$1.5M
Dietary fiber to mitigate antibiotic-induced microbiome dysbiosis: a multi-omics approachR21AT010366 · NCCIH · BROWN UNIVERSITY · PI BELENKY, PETER · 2019 to 2020
$447k
NCCIH NIH HHS R21 AT010366NIGMS NIH HHS P20 GM109035NIGMS NIH HHS P20 GM121344NIGMS NIH HHS T32 GM128596
6 · The paper itself

Abstract

Dietary composition and antibiotic use have major impacts on the structure and function of the gut microbiome, often resulting in dysbiosis. Despite this, little research has been done to explore the role of host diet as a determinant of antibiotic-induced microbiome disruption. Here, we utilize a multi-omic approach to characterize the impact of Western-style diet consumption on ciprofloxacin-induced changes to gut microbiome structure and transcriptional activity. We found that Western diet consumption dramatically increased

Indexed as

antibioticsdietdysbiosismetagenomicsmetatranscriptomics

Identifiers

PMID32723789
PMCPMC7394352
OpenAlexW3046037231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.