Evidence map›Paper›PMID 32722990›Full record

ArticleVirulence2020

Characteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study.

Chao Yu, Miao Zhou, Yang Liu, Tinglin Guo, Chongyang Ou, Liye Yang, Yan Li, Dongliang Li, Xinyu Hu, Li Shuai and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Virulence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Out-of-hospital cardiac arrest and in-hospital mortality among COVID-19 patients: A population-based retrospective cohort study.Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Disease markers · 2022
    Article
  15. ABO blood grouping and COVID-19: a hospital-based study in Eastern India.The Egyptian journal of medical human genetics · 2022
    Article
  16. Article
  17. Article
  18. Critical appraisal of the mechanisms of gastrointestinal and hepatobiliary infection by COVID-19.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Article
  19. Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chao YuDepartment of Respiratory and Critical Care Medicine, Naval Hospital of Eastern Theater of PLA ,Zhoushan, Zhejiang, P. R. China.
Miao ZhouDepartment of Anesthesiology and SICU, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University , Shanghai, P. R. China.
Yang LiuDepartment of Anesthesiology, Changzheng Hospital, Second Military Medical University , Shanghai, P. R. China.
Tinglin GuoDepartment of Respiratory and Critical Care Medicine, Naval Hospital of Eastern Theater of PLA ,Zhoushan, Zhejiang, P. R. China.
Chongyang OuDepartment of Respiratory and Critical Care Medicine, Naval Hospital of Eastern Theater of PLA ,Zhoushan, Zhejiang, P. R. China.
Liye YangDepartment of Anesthesiology, Changzheng Hospital, Second Military Medical University , Shanghai, P. R. China.
Yan LiDepartment of Orthopedics, Ningxiang People's Hospital, Changsha City , Hunan, P. R. China.
Dongliang LiDepartment of Hepatobiliary Medicine, The 900th Hospital of the People's Liberation Army Joint Service Force , Fuzhou, Fujian, P. R. China.
Xinyu HuGraduate School, Hebei North University , Zhangjiakou, Hebei, P. R. China.
Li ShuaiDepartment of Respiratory and Critical Care Medicine, Naval Hospital of Eastern Theater of PLA ,Zhoushan, Zhejiang, P. R. China.
Bin WangDepartment of Oncology, Changhai Hospital, Second Military Medical University , Shanghai, P. R. China.
Zui ZouDepartment of Anesthesiology, Changzheng Hospital, Second Military Medical University , Shanghai, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel coronavirus disease 2019 (COVID-19), caused by novel coronavirus SARS-CoV-2, has spread globally since the end of 2019. Asymptomatic carriers are of great concern as they can undermine the interventions to stop the pandemic. However, there is limited information about the characteristics and outcomes of the asymptomatic patients. Therefore, we conducted this retrospective study and retrieved data of 79 asymptomatic COVID-19 patients at admission from three designated hospitals in Wuhan, China. The asymptomatic patients could happen at any age, ranged from 9 to 96 years. These patients also had lower levels of alanine aminotransferase and C-reactive protein. Patchy shadowing was the most common manifestation in computed tomography scan. Some asymptomatic carriers developed mild or moderate symptoms during hospitalization. Age and comorbidities, especially hypertension, may be predictive factors for symptom development in the initially asymptomatic carriers at admission. Early detection and treatment for these presymptomatic patients before symptom onset can shorten the communicable period for the coronavirus and reduce the occurrence of severe cases.

Indexed as

BetacoronavirusAdolescentAdultAgedAged, 80 and overAsymptomatic InfectionsChildChinaCoronavirus InfectionsCOVID-19Disease ProgressionFemaleHumansMaleMiddle AgedPandemicsasymptomaticCOVID-19early treatmenthypertension

Identifiers

PMID32722990
PMCPMC7550018

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.