Evidence map›Paper›PMID 32722889›Full record

ArticleSynapse (New York, N.Y.)2021

Development and evaluation of [

Jogeshwar Mukherjee, Christopher Liang, Krystal K Patel, Phuc Q Lam, Rommani Mondal

Open access · greenAbstract read
In one paragraph

Article in Synapse (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 23 citations in OpenAlex.

  1. Evaluation of [Acta neuropathologica communications · 2026
    Article
  2. Article
  3. Article
  4. Evaluation of [Research square · 2026
    Article
  5. Synthesis and Evaluation of Radioiodinated [Journal of labelled compounds & radiopharmaceuticals · 2026
    Article
  6. [Synapse (New York, N.Y.) · 2025
    Article
  7. Reduction in [Brain research · 2025
    Article
  8. [Biomolecules · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. [Neurology international · 2024
    Article
  13. Article
  14. [Molecules (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Article
  17. Development of [Molecules (Basel, Switzerland) · 2023
    Article
  18. Article
  19. [Molecules (Basel, Switzerland) · 2022
    Article
  20. NRM 2021 Abstract Booklet.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jogeshwar MukherjeePreclinical Imaging, Department of Radiological Sciences, University of California, Irvine, CA, USA.ORCID 0000-0003-1009-877X
Christopher LiangPreclinical Imaging, Department of Radiological Sciences, University of California, Irvine, CA, USA.
Krystal K PatelPreclinical Imaging, Department of Radiological Sciences, University of California, Irvine, CA, USA.
Phuc Q LamPreclinical Imaging, Department of Radiological Sciences, University of California, Irvine, CA, USA.
Rommani MondalPreclinical Imaging, Department of Radiological Sciences, University of California, Irvine, CA, USA.
University of California, Irvine · US

Funding

Research Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI REIMAN, ERIC MICHAEL · 2001 to 2020
$32.5M
National Brain and Tissue Resource for Parkinson's Disease and Related DisordersU24NS072026 · NINDS · BANNER SUN HEALTH RESEARCH INSTITUTE · PI BEACH, THOMAS G · 2011 to 2015
$7.8M
PET Imaging Agents for Nicotinic a4b2 ReceptorsR01AG029479 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI MUKHERJEE, JOGESHWAR · 2007 to 2017
$2.6M
PET Imaging agents for a4b2 Nicotinic ReceptorsRF1AG029479 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHRISTIAN, BRADLEY T, MUKHERJEE, JOGESHWAR · 2019 to 2020
$2.2M
NIA NIH HHS P30 AG019610NIA NIH HHS R01 AG029479NIA NIH HHS RF1 AG029479NINDS NIH HHS U24 NS072026
6 · The paper itself

Abstract

objectiveAlzheimer's disease (AD) is a neurodegenerative disease characterized by aggregation of Tau protein into paired helical filaments causing neurofibrillary tangles (NFT) in the brain. The aim of this study was to develop and evaluate the effectiveness of a novel radioiodinated tracer, 6-[

methodsRadiosynthesis of [

results[

conclusion[

Indexed as

AgedAged, 80 and overAlzheimer DiseaseAutopsyAutoradiographyBinding SitesBrainDrug DevelopmentFemaleHumansIodine RadioisotopesIsoquinolinesMaleMiddle AgedPyridinestau ProteinsIodine-125Iodine RadioisotopesisoquinolineIsoquinolinesMAPT protein, humanMK-6240Pyridinestau Proteins[125I]IPPIAlzheimer's diseasehuman Tauneurofibrillary tangles

Identifiers

PMID32722889
PMCPMC8373522
OpenAlexW3045633283

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.