Evidence map›Paper›PMID 32722823›Full record

ArticleAmerican journal of perinatology2022

Term Labor Induction and Cesarean Delivery Risk among Obese Women with and without Comorbidities.

Kimberly B Glazer, Valery A Danilack, Alison E Field, Erika F Werner, David A Savitz

Abstract read
In one paragraph

Article in American journal of perinatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kimberly B GlazerDepartment of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0002-3318-9802
Valery A DanilackDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island.ORCID 0000-0001-8165-3457
Alison E FieldDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island.
Erika F WernerDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island.ORCID 0000-0002-0938-582X
David A SavitzDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island.
Brown University · USProvidence College · US

Funding

AHRQ HHS K01 HS025013
6 · The paper itself

Abstract

objectiveFindings of the recent ARRIVE (A Randomized Trial of Induction Versus Expectant Management) trial, showing reduced cesarean risk with elective labor induction among low-risk nulliparous women at 39 weeks' gestation, have the potential to change interventional delivery practices but require examination in wider populations. The aim of this study was to identify whether term induction of labor was associated with reduced cesarean delivery risk among women with obesity, evaluating several maternal characteristics associated with obesity, induction, and cesarean risk. STUDY

designWe studied administrative records for 66,280 singleton, term births to women with a body mass index ≥30, without a prior cesarean delivery, in New York City from 2008 to 2013. We examined elective inductions in 39 and 40 weeks' gestation and calculated adjusted risk ratios for cesarean delivery risk, stratified by parity and maternal age. We additionally evaluated medically indicated inductions at 37 to 40 weeks among women with obesity and diabetic or hypertensive disorders, comorbidities that are strongly associated with obesity.

resultsElective induction of labor was associated with a 25% (95% confidence interval: 19-30%) lower adjusted risk of cesarean delivery as compared with expectant management at 39 weeks of gestation and no change in risk at 40 weeks. Patterns were similar when stratified by parity and maternal age. Risk reductions in week 39 were largest among women with a prior vaginal delivery. Women with comorbidities had reduced cesarean risk with early term induction and in 39 weeks.

conclusionLabor induction at 39 weeks was consistently associated with reduced risk of cesarean delivery among women with obesity regardless of parity, age, or comorbidity status. Cesarean delivery findings from induction trials at 39 weeks among low-risk nulliparous women may generalize more broadly across the U.S. obstetric population, with potentially larger benefit among women with a prior vaginal delivery. KEY POINTS: · We found reduced cesarean risk with induction at 39 weeks.. · Results were consistent for age and comorbidity subgroups.. · Risk reductions were largest among multiparous women..

Indexed as

Labor, InducedAdultBody Mass IndexCesarean SectionComorbidityElective Surgical ProceduresFemaleGestational AgeHumansLabor, ObstetricNew York CityObesityParityPregnancyYoung Adult

Identifiers

PMID32722823
PMCPMC13352593
OpenAlexW3045789566

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.