Evidence map›Paper›PMID 32722695›Full record

ArticlePloS one2020

The risk factors associated with treatment-related mortality in 16,073 kidney transplantation-A nationwide cohort study.

Hyunji Choi, Woonhyoung Lee, Ho Sup Lee, Seom Gim Kong, Da Jung Kim, Sangjin Lee, Haeun Oh, Ye Na Kim, Soyoung Ock, Taeyun Kim and 5 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Hyunji ChoiDepartment of Laboratory Medicine, Kosin University College of Medicine, Busan, South Korea.ORCID 0000-0002-6453-7099
Woonhyoung LeeDepartment of Laboratory Medicine, Kosin University College of Medicine, Busan, South Korea.
Ho Sup LeeDepartment of Hematology-Oncology, Kosin University College of Medicine, Busan, South Korea.
Seom Gim KongDepartment of Pediatrics, Kosin University College of Medicine, Busan, South Korea.
Da Jung KimDepartment of Hematology-Oncology, Kosin University College of Medicine, Busan, South Korea.
Sangjin LeeGraduate School, Department of Statistics, Pusan National University, Busan, South Korea.
Haeun OhDepartment of Laboratory Medicine, Kosin University College of Medicine, Busan, South Korea.
Ye Na KimDepartment of Nephrology, Kosin University College of Medicine, Busan, South Korea.
Soyoung OckDepartment of Internal Medicine, Kosin University College of Medicine, Busan, South Korea.
Taeyun KimDepartment of Internal Medicine, Kosin University College of Medicine, Busan, South Korea.ORCID 0000-0001-7786-5051
Min-Jeong ParkDepartment of Laboratory Medicine, Hallym University College of Medicine, Seoul, South Korea.
Wonkeun SongDepartment of Laboratory Medicine, Hallym University College of Medicine, Seoul, South Korea.
John Hoon RimDepartment of Pharmacology, Yonsei University College of Medicine, Seoul, South Korea.
Jong-Han LeeDepartment of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, South Korea.
Seri JeongDepartment of Laboratory Medicine, Hallym University College of Medicine, Seoul, South Korea.ORCID 0000-0002-4199-7033
Kosin University · KRHallym University · KRYonsei University · KRPusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mortality at an early stage after kidney transplantation is a catastrophic event. Treatment-related mortality (TRM) within 1 or 3 months after kidney transplantation has been seldom reported. We designed a retrospective observational cohort study using a national population-based database, which included information about all kidney recipients between 2003 and 2016. A total of 16,073 patients who underwent kidney transplantation were included. The mortality rates 1 month (early TRM) and 3 months (TRM) after transplantation were 0.5% (n = 74) and 1.0% (n = 160), respectively. Based on a multivariate analysis, older age (hazard ratio [HR] = 1.06; P < 0.001), coronary artery disease (HR = 3.02; P = 0.002), and hemodialysis compared with pre-emptive kidney transplantation (HR = 2.53; P = 0.046) were the risk factors for early TRM. Older age (HR = 1.07; P < 0.001), coronary artery disease (HR = 2.88; P < 0.001), and hemodialysis (HR = 2.35; P = 0.004) were the common independent risk factors for TRM. In contrast, cardiac arrhythmia (HR = 1.98; P = 0.027) was associated only with early TRM, and fungal infection (HR = 2.61; P < 0.001), and epoch of transplantation (HR = 0.34; P < 0.001) were the factors associated with only TRM. The identified risk factors should be considered in patient counselling, selection, and management to prevent TRM.

Indexed as

Kidney TransplantationAdultAgedAge FactorsCohort StudiesCoronary Artery DiseaseFemaleGraft vs Host DiseaseHumansMaleMiddle AgedProportional Hazards ModelsRenal DialysisRisk FactorsSurvival RateTransplantation, Homologous

Identifiers

PMID32722695
PMCPMC7386583
OpenAlexW3045707979

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.