Evidence map›Paper›PMID 32722664›Full record

ArticlePediatric research2021

Residential dust lead levels and the risk of childhood lead poisoning in United States children.

Joseph M Braun, Kimberly Yolton, Nicholas Newman, David E Jacobs, Mark Taylor, Bruce P Lanphear

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Pediatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 3 countries.

Joseph M BraunDepartment of Epidemiology, Brown University, Providence, 02912, RI, USA. joseph_braun_1@brown.edu.
Kimberly YoltonDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, 45229, OH, USA.
Nicholas NewmanDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, 45229, OH, USA.
David E JacobsNational Center for Healthy Housing and University of Illinois at Chicago, Chicago, 60612, IL, USA.
Mark TaylorDepartment of Environmental Sciences, Faculty of Science and Engineering, Macquarie University, North Ryde, Sydney, NSW, 2109, Australia.
Bruce P LanphearFaculty of Health Sciences, Simon Fraser University, Burnaby, BCV5A 1S6, Canada.
Brown University · USMacquarie University · AUSimon Fraser University · CAUniversity of Cincinnati · USUniversity of Cincinnati Medical Center · USUniversity of Illinois Chicago · US

Funding

Study of Prevalent Neurotoxicants in ChildrenP01ES011261 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI LANPHEAR, BRUCE P · 2001 to 2006
$6.4M
A Community-Based Trial to Prevent Lead Poisoning and InjuriesR01ES014575 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI YOLTON, KIMBERLY · 2007 to 2011
$2.9M
NIEHS NIH HHS P01 ES011261NIEHS NIH HHS R01 ES014575
6 · The paper itself

Abstract

backgroundThe United States Environmental Protection Agency (EPA) recently lowered residential floor and windowsill dust lead hazard standards, but maintained previous post-abatement clearance standards. We examined whether the discrepancy in these regulations places children at higher risk of lead poisoning.

methodsIn 250 children from Cincinnati, Ohio (2004-2008) living in homes built before 1978, we measured residential floor and windowsill dust lead loadings and blood lead concentrations at ages 1 and 2 years. Using linear regression with generalized estimating equations, we estimated covariate-adjusted associations of dust lead levels with blood lead concentrations and risk of lead poisoning.

resultsAn increase in floor dust lead from 10 (revised dust lead hazard standard) to 40 μg/ft

conclusionsThe EPA's residential dust lead regulations place children at increased risk of lead poisoning. We recommend adopting more protective dust lead standards. IMPACT: We determined whether children are at increased risk of lead poisoning with the 2019 EPA residential post-abatement lead clearance standards being higher than dust lead hazard standards. In this observational study, 2019 EPA dust lead clearance standards were associated with increased risk of lead poisoning compared to the revised dust lead hazard standard. Both EPA standards were associated with increased risk of lead poisoning compared to more stringent standards employed in our study. Extrapolating our findings to US children, the 2019 EPA dust lead clearance standards could place up to 36,700 children at risk of lead poisoning.

Indexed as

Family CharacteristicsAdultChildDustFemaleHumansLeadLead PoisoningLongitudinal StudiesMaleOhioPregnancyRandomized Controlled Trials as TopicRisk FactorsUnited StatesDustLead

Identifiers

PMID32722664
OpenAlexW3045839343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.