Evidence map›Paper›PMID 32722476›Full record

ArticleCancers2020

Prognostic Significance of CD105- and CD31-Assessed Microvessel Density in Paired Biopsies and Surgical Samples of Laryngeal Carcinoma.

Gino Marioni, Leonardo Franz, Giancarlo Ottaviano, Giacomo Contro, Giulia Tealdo, Alessandro Carli, Anna Chiara Frigo, Piero Nicolai, Lara Alessandrini

Abstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Endoglin in head and neck neoplasms.Frontiers in medicine · 2023
    Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gino MarioniDepartment of Neuroscience-DNS, Otolaryngology Section, University of Padova, 35128 Padova, Italy.ORCID 0000-0001-8751-0588
Leonardo FranzDepartment of Neuroscience-DNS, Otolaryngology Section, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-2306-4088
Giancarlo OttavianoDepartment of Neuroscience-DNS, Otolaryngology Section, University of Padova, 35128 Padova, Italy.
Giacomo ControDepartment of Neuroscience-DNS, Otolaryngology Section, University of Padova, 35128 Padova, Italy.
Giulia TealdoDepartment of Neuroscience-DNS, Otolaryngology Section, University of Padova, 35128 Padova, Italy.ORCID 0000-0003-3625-1568
Alessandro CarliDepartment of Neuroscience-DNS, Otolaryngology Section, University of Padova, 35128 Padova, Italy.
Anna Chiara FrigoDepartment of Cardiac-Thoracic-Vascular Sciences and Public Health, Padova University, 35128 Padova, Italy.ORCID 0000-0001-9705-4459
Piero NicolaiDepartment of Neuroscience-DNS, Otolaryngology Section, University of Padova, 35128 Padova, Italy.
Lara AlessandriniDepartment of Medicine-DIMED, University of Padova, 35128 Padova, Italy.

Funding

Università degli Studi di Padova DOR1951845/19
6 · The paper itself

Abstract

Small pretreatment laryngeal biopsies may not fully represent a tumor's biological profile. This study on laryngeal squamous cell carcinoma (LSCC) aimed to investigate the prognostic role of CD105- and CD31-assessed microvessel density (MVD) in paired biopsies and surgical specimens and the association and discrepancy between CD105- and CD31-assessed MVD in biopsies and surgical specimens. CD105- and CD31-assessed MVD was analyzed in paired biopsies and surgical specimens of 45 consecutive cases of LSCC. In the LSCC biopsies and surgical specimens, median CD105-assessed MVD was significantly higher in N+ than in N0 cases (

Indexed as

angiogenesisbiopsyCD105CD31laryngeal squamous cell carcinomaprognosissurgical specimen

Identifiers

PMID32722476
PMCPMC7465153

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.