Evidence map›Paper›PMID 32722455›Full record

ReviewAntibiotics (Basel, Switzerland)2020

Current Antimycotics, New Prospects, and Future Approaches to Antifungal Therapy.

Gina Wall, Jose L Lopez-Ribot

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
2.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 168 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Emerging Applications of Triazole Antifungal Drugs.International journal of molecular sciences · 2026
    Review
  13. Article
  14. Article
  15. Review
  16. Bioactive Constituents ofDrug design, development and therapy · 2026
    Review
  17. Article
  18. Article
  19. Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gina WallDepartment of Biology and The South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.
Jose L Lopez-RibotDepartment of Biology and The South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.ORCID 0000-0003-1992-3270
Texas Center for Infectious Disease · US

Funding

Screening a Target-Based Repurposing Library for Activity against Fungal Pathogens and Subsequent Preclinical Development of Leading CandidatesR33AI140823 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI LOPEZ-RIBOT, JOSE L., WORMLEY, FLOYD L. · 2021 to 2023
$1.3M
Screening a Target-Based Repurposing Library for Activity against Fungal Pathogens and Subsequent Preclinical Development of Leading CandidatesR21AI140823 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI LOPEZ-RIBOT, JOSE L., WORMLEY, FLOYD L. · 2019 to 2019
$313k
Margaret Batts Tobin Foundation No numberNIAID NIH HHS R21 AI140823NIAID NIH HHS R33 AI140823NIH HHS R21AI140823
6 · The paper itself

Abstract

Fungal infections represent an increasing threat to a growing number of immune- and medically compromised patients. Fungi are eukaryotic organisms and, as such, there is a limited number of selective targets that can be exploited for antifungal drug development. This has also resulted in a very restricted number of antifungal drugs that are clinically available for the treatment of invasive fungal infections at the present time-polyenes, azoles, echinocandins, and flucytosine. Moreover, the utility of available antifungals is limited by toxicity, drug interactions and the emergence of resistance, which contribute to high morbidity and mortality rates. This review will present a brief summary on the landscape of current antifungals and those at different stages of clinical development. We will also briefly touch upon potential new targets and opportunities for novel antifungal strategies to combat the threat of fungal infections.

Indexed as

antifungal agentsantifungal drug developmentfungal infections

Identifiers

PMID32722455
PMCPMC7460292
OpenAlexW3044266761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.