Evidence map›Paper›PMID 32722448›Full record

ArticleMicromachines2020

The Influence of Electric Field Intensity and Particle Length on the Electrokinetic Transport of Cylindrical Particles Passing through Nanopore.

Liuyong Shi, Xiaohan He, Jian Ge, Teng Zhou, Ting Li, Sang Woo Joo

Abstract read
In one paragraph

Article in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liuyong ShiMechanical and Electrical Engineering College, Hainan University, Haikou 570228, China.
Xiaohan HeMechanical and Electrical Engineering College, Hainan University, Haikou 570228, China.
Jian GeMechanical and Electrical Engineering College, Hainan University, Haikou 570228, China.
Teng ZhouMechanical and Electrical Engineering College, Hainan University, Haikou 570228, China.ORCID 0000-0002-8744-9083
Ting LiInstitute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China.
Sang Woo JooSchool of Mechanical Engineering, Yeungnam University, Gyongsan 38541, Korea.

Funding

Hainan Provincial Natural Science Foundation of China 519MS021 and 2019RC032National Natural Science Foundation of China 61964006 and 51605124
6 · The paper itself

Abstract

The electric transport of nanoparticles passing through nanopores leads to a change in the ion current, which is essential for the detection technology of DNA sequencing and protein determination. In order to further illustrate the electrokinetic transport mechanism of particles passing through nanopores, a fully coupled continuum model is constructed by using the arbitrary Lagrangian-Eulerian (ALE) method. The model consists of the electric field described by the Poisson equation, the concentration field described by Nernst-Planck equation, and the flow field described by the Navier-Stokes equation. Based on this model, the influence of imposed electric field and particle length on the electrokinetic transport of cylindrical particles is investigated. It is found firstly the translation velocities for the longer particles remain constant when they locate inside the nanopore. Both the ion current blockade effect and the ion current enhancement effect occur when cylindrical particles enter and exit the nanopore, respectively, for the experimental parameters employed in this research. Moreover, the particle translation velocity and current fluctuation amplitude are dominated by the electric field intensity, which can be used to adjust the particle transmission efficiency and the ion current detectability. In addition, the increase in particle length changes the particle position corresponding to the peak value of the ion current, which contributes to distinguishing particles with different lengths as well.

Indexed as

arbitrary Lagrangian–Eulerian (ALE)electrokineticsmechanismnanofluidicsnanopore

Identifiers

PMID32722448
PMCPMC7463976

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.