Evidence map›Paper›PMID 32722439›Full record

ArticleAnimals : an open access journal from MDPI2020

Comparative Transcriptomic Analysis of the Pituitary Gland between Cattle Breeds Differing in Growth: Yunling Cattle and Leiqiong Cattle.

Xubin Lu, Abdelaziz Adam Idriss Arbab, Zhipeng Zhang, Yongliang Fan, Ziyin Han, Qisong Gao, Yujia Sun, Zhangping Yang

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xubin LuCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0001-6286-1517
Abdelaziz Adam Idriss ArbabCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Zhipeng ZhangCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Yongliang FanCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Ziyin HanCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Qisong GaoCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Yujia SunJoint International Research Laboratory of Agriculture and Agri-Product Safety, Yangzhou University, Yangzhou 225009, China.
Zhangping YangCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0002-5479-8447
Yangzhou University · CN

Funding

National Natural Science Foundation of China 31872324National Natural Science Foundation of China 31902147The Earmarked Fund for Jiangsu Agricultural Industry Technology System : JATS [2019]446
6 · The paper itself

Abstract

The hypothalamic-pituitary-thyroid (HPT) axis hormones regulate the growth and development of ruminants, and the pituitary gland plays a decisive role in this process. In order to identify pivotal genes in the pituitary gland that could affect the growth of cattle by regulating the secretion of hormones, we detected the content of six HPT hormones related to growth in the plasma of two cattle breeds (Yunling and Leiqiong cattle, both also known as the zebu cattle) with great differences in growth and compared the transcriptome data of their pituitary glands. Our study found that the contents of GH, IGF, TSH, thyroxine, triiodothyronine, and insulin were significantly different between the two breeds, which was the main cause of the difference in growth; 175 genes were identified as differentially expressed genes (DEGs). Functional association analyses revealed that DEGs were mainly involved in the process of transcription and signal transduction. Combining the enrichment analysis and protein interaction analysis, eight DEGs were predicted to control the growth of cattle by affecting the expression of growth-related hormones in the pituitary gland. In summary, our results suggested that

Indexed as

growthhormonesLeiqiong cattlepituitary glandtranscriptomeYunling cattle

Identifiers

PMID32722439
PMCPMC7460210
OpenAlexW3045326167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.