Evidence map›Paper›PMID 32722403›Full record

ArticlePharmaceutics2020

Polymer Nanomedicines with Ph-Sensitive Release of Dexamethasone for the Localized Treatment of Inflammation.

Alena Libánská, Eva Randárová, Franck Lager, Gilles Renault, Daniel Scherman, Tomáš Etrych

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alena LibánskáInstitute of Macromolecular Chemistry, Czech Academy of Sciences, 162 06 Prague, Czech Republic.
Eva RandárováInstitute of Macromolecular Chemistry, Czech Academy of Sciences, 162 06 Prague, Czech Republic.
Franck LagerInstitut Cochin, Université de Paris, INSERM, CNRS, 75014 Paris, France.
Gilles RenaultInstitut Cochin, Université de Paris, INSERM, CNRS, 75014 Paris, France.
Daniel SchermanUnité de Technologies Chimiques et Biologiques pour la Santé, Faculté de Pharmacie, Université de Paris, CNRS UMR 8258, Inserm U1267, 75270 Paris, France.
Tomáš EtrychInstitute of Macromolecular Chemistry, Czech Academy of Sciences, 162 06 Prague, Czech Republic.ORCID 0000-0001-5908-5182
Centre National de la Recherche Scientifique · FRCzech Academy of Sciences, Institute of Macromolecular Chemistry · CZ

Funding

France Life Imaging ANR-11-INBS-0006Grantová Agentura České Republiky 19-00956YMinisterstvo Školství, Mládeže a Tělovýchovy BIOCEV-FAR LQ1604Ministerstvo Školství, Mládeže a Tělovýchovy CZ.1.05/1.1.00/02.0109Ministerstvo Školství, Mládeže a Tělovýchovy MSMT LTAUSA18083
6 · The paper itself

Abstract

Polymer-drug conjugates have several advantages in controlled drug delivery to inflammation as they can accumulate and release the drug in inflamed tissues or cells, which could circumvent the shortcomings of current therapy. To improve the therapeutic potential of polymer-drug conjugates in joint inflammation, we synthesized polymer conjugates based on

Indexed as

adjuvant-induced arthritisdexamethasonedrug deliveryHPMAinflammationpassive targetingpolymer conjugate

Identifiers

PMID32722403
PMCPMC7465548
OpenAlexW3045169924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.