Evidence map›Paper›PMID 32722325›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

Sevanol and Its Analogues: Chemical Synthesis, Biological Effects and Molecular Docking.

Olga A Belozerova, Dmitry I Osmakov, Andrey Vladimirov, Sergey G Koshelev, Anton O Chugunov, Yaroslav A Andreev, Victor A Palikov, Yulia A Palikova, Elvira R Shaykhutdinova, Artem N Gvozd and 4 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Dual Modulator of ASIC Channels and GABAInternational journal of molecular sciences · 2023
    Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Olga A BelozerovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Dmitry I OsmakovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0001-6588-5012
Andrey VladimirovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Sergey G KoshelevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Anton O ChugunovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0003-1331-3949
Yaroslav A AndreevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-7628-0980
Victor A PalikovBranch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 6 Nauki Avenue, 142290 Pushchino, Russia.
Yulia A PalikovaBranch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 6 Nauki Avenue, 142290 Pushchino, Russia.
Elvira R ShaykhutdinovaBranch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 6 Nauki Avenue, 142290 Pushchino, Russia.
Artem N GvozdFederal State Budgetary Institution «Scientific Center of Biomedical Technologies of Federal Medical and Biological Agency» (FSBI SCBT FMBA of Russia), 1 Svetlye Gory, Moscovskaya Oblast, 143442 Krasnogorskiy Rayon, Russia.
Igor A DyachenkoBranch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 6 Nauki Avenue, 142290 Pushchino, Russia.
Roman G EfremovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Vadim S KublitskiShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Sergey A KozlovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-0242-4240
Institute of Bioorganic Chemistry · RUNational Research University Higher School of Economics · RUSechenov University · RU

Funding

Basic Research Program at the National Research University Higher School of Economics and Russian Academic Excellence 5-100Russian Academy of Sciences "Postgenomic technologies and promising solutions in biomedicine" programRussian Foundation for Basic Research 19-04-00350Russian Science Foundation 18-14-00138
6 · The paper itself

Abstract

Among acid-sensing ion channels (ASICs), ASIC1a and ASIC3 subunits are the most widespread and prevalent in physiological and pathophysiological conditions. They participate in synaptic plasticity, learning and memory, as well as the perception of inflammatory and neurological pain, making these channels attractive pharmacological targets. Sevanol, a natural lignan isolated from

Indexed as

acid-sensing ion channelanalgesiaelectrophysiologylignanmolecular dockingnociceptionsevanoltotal synthesis

Identifiers

PMID32722325
PMCPMC7466040
OpenAlexW3044645703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.