Evidence map›Paper›PMID 32722221›Full record

ArticleMolecules (Basel, Switzerland)2020

Preclinical Evaluation of NHS-Activated Gold Nanoparticles Functionalized with Bombesin or Neurotensin-Like Peptides for Targeting Colon and Prostate Tumours.

Livia Elena Chilug, Dana Niculae, Radu Anton Leonte, Alexandrina Nan, Rodica Turcu, Cosmin Mustaciosu, Radu Marian Serban, Vasile Lavric, Gina Manda

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Neurotensin and Its Involvement in Female Hormone-Sensitive Cancers.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Livia Elena ChilugRadiopharmaceutical Research Centre, Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering, 30 Reactorului Street, Magurele, 077125 Ilfov, Romania.
Dana NiculaeRadiopharmaceutical Research Centre, Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering, 30 Reactorului Street, Magurele, 077125 Ilfov, Romania.ORCID 0000-0002-4769-843X
Radu Anton LeonteRadiopharmaceutical Research Centre, Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering, 30 Reactorului Street, Magurele, 077125 Ilfov, Romania.
Alexandrina NanNational Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Street, 400293 Cluj-Napoca, Romania.ORCID 0000-0001-6898-2723
Rodica TurcuNational Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Street, 400293 Cluj-Napoca, Romania.ORCID 0000-0002-6355-8381
Cosmin MustaciosuRadiopharmaceutical Research Centre, Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering, 30 Reactorului Street, Magurele, 077125 Ilfov, Romania.
Radu Marian SerbanRadiopharmaceutical Research Centre, Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering, 30 Reactorului Street, Magurele, 077125 Ilfov, Romania.
Vasile LavricFaculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Polizu Street, 011061 Bucharest, Romania.ORCID 0000-0001-6196-4186
Gina MandaVictor Babes National Institute of Pathology, 99-101 Splaiul Independentei Street, 050096 Bucharest, Romania.ORCID 0000-0002-9706-1883
Horia Hulubei National Institute for R and D in Physics and Nuclear Engineering · RONational Institute for Research and Development of Isotopic and Molecular Technologies · ROInstitutul National Victor Babes · ROUniversitatea Națională de Știință și Tehnologie Politehnica București · ROUniversity of Bucharest · RO

Funding

Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii 64PCCDI/2017
6 · The paper itself

Abstract

Recent advances and large-scale use of hybrid imaging modalities like PET-CT have led to the necessity of improving nano-drug carriers that can facilitate both functional and metabolic screening in nuclear medicine applications. In this study, we focused on the evaluation of four potential imaging nanoparticle structures labelled with the

Indexed as

AnimalsBiological AvailabilityBombesinCell Line, TumorCell ProliferationCell SurvivalColonic NeoplasmsGallium RadioisotopesGoldHT29 CellsHumansMaleMetal NanoparticlesMiceNeoplasm TransplantationNeurokinin BBombesinGallium RadioisotopesGoldNeurokinin Bneuromedin Bneuromedin NNeurotensinPeptide FragmentsPeptidesReceptors, BombesinReceptors, Neurotensin68Gabombesincolon cancerdrug deliverygold nanoparticlesneurotensinPET imagingprostate cancer

Identifiers

PMID32722221
PMCPMC7435928
OpenAlexW3044859067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.