Evidence map›Paper›PMID 32722017›Full record

ArticleBiomedicines2020

The Role of GPR120 Receptor in Essential Fatty Acids Metabolism in Schizophrenia.

Joanna Rog, Anna Błażewicz, Dariusz Juchnowicz, Agnieszka Ludwiczuk, Ewa Stelmach, Małgorzata Kozioł, Michal Karakula, Przemysław Niziński, Hanna Karakula-Juchnowicz

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
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  5. Brain sciences · 2022
    Article
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Joanna Rog1st Department of Psychiatry, Psychotherapy and Early Intervention, Medical University of Lublin, 20-439 Lublin, Poland.
Anna BłażewiczChair of Chemistry, Department of Analytical Chemistry, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0001-9758-5831
Dariusz JuchnowiczDepartment of Psychiatric Nursing, Medical University of Lublin, 20-093 Lublin, Poland.
Agnieszka LudwiczukIndependent Laboratory of Natural Products Chemistry, Department of Pharmacognosy, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0003-1108-613X
Ewa Stelmach2nd Department of Psychiatry and Psychiatric Rehabilitation, Medical University of Lublin, 20-439 Lublin, Poland.
Małgorzata KoziołChair and Department of Medical Microbiology, Medical University of Lublin; 20-093 Lublin, Poland.
Michal KarakulaStudent Research Team from Department of Analytical Chemistry, Medical University of Lublin, 20-093 Lublin, Poland.
Przemysław NizińskiChair of Chemistry, Department of Analytical Chemistry, Medical University of Lublin, 20-093 Lublin, Poland.
Hanna Karakula-Juchnowicz1st Department of Psychiatry, Psychotherapy and Early Intervention, Medical University of Lublin, 20-439 Lublin, Poland.
Medical University of Lublin · PL

Funding

Uniwersytet Medyczny w Lublinie DS192
6 · The paper itself

Abstract

A growing body of evidence confirms abnormal fatty acid (FAs) metabolism in the pathophysiology of schizophrenia. Omega-3 polyunsaturated fatty acids (PUFAs) are endogenous ligands of the G protein-coupled receptors, which have anti-inflammatory properties and are a therapeutic target in many diseases. No clinical studies are concerned with the role of the GPR120 signaling pathway in schizophrenia. The aim of the study was to determine the differences in PUFA nutritional status and metabolism between patients with schizophrenia (SZ group) and healthy individuals (HC group). The study included 80 participants (40 in the SZ group, 40 in the HC group). There were no differences in serum GPR120 and PUFA concentrations and PUFA intake between the examined groups. In the HC group, there was a relationship between FAs in serum and GPR120 concentration (

Indexed as

FFAR4GPR120G protein-coupled receptorslong-chain fatty acidsnutritional psychiatryomega-3polyunsaturated fatty acidsschizophrenia

Identifiers

PMID32722017
PMCPMC7459811
OpenAlexW3044857968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.