Evidence map›Paper›PMID 32721788›Full record

ArticleDrug and alcohol dependence2020

Correlates of alcohol use disorder pharmacotherapy receipt in medically insured patients.

Alexander Rittenberg, Anika L Hines, Anika A H Alvanzo, Geetanjali Chander

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  3. Observational
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  11. Alcohol pharmacotherapy dispensing trends in Australia between 2006 and 2023.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alexander RittenbergJohns Hopkins University School of Medicine, 1830 E Monument Street, Baltimore, MD, 21287, United States. Electronic address: alexander.rittenberg@vcuhealth.org.
Anika L HinesJohns Hopkins University School of Medicine, 1830 E Monument Street, Baltimore, MD, 21287, United States. Electronic address: anika.hines@vcuhealth.org.
Anika A H AlvanzoJohns Hopkins University School of Medicine, 1830 E Monument Street, Baltimore, MD, 21287, United States. Electronic address: aalvanzo.ucg@gmail.com.
Geetanjali ChanderJohns Hopkins University School of Medicine, 1830 E Monument Street, Baltimore, MD, 21287, United States. Electronic address: gchande1@jhmi.edu.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Anna Palmer Durbin · 2012 to 2026
$67.0M
BEHAVIORAL RESEARCH IN HEART &VASCULAR DISEASET32HL007180 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MARUTHUR, NISA M · 1985 to 2020
$11.4M
Mentoring and Patient Oriented Research at the Nexus of Unhealthy Alcohol Use and HIVK24AA027483 · NIAAA · UNIVERSITY OF WASHINGTON · PI GEETANJALI CHANDER · 2019 to 2026
$1.3M
NHLBI NIH HHS T32 HL007180NIAAA NIH HHS K24 AA027483NIAID NIH HHS P30 AI094189
6 · The paper itself

Abstract

backgroundAlcohol use disorder is a highly prevalent disease with multiple medications available for treatment. The overall prevalence of patients receiving pharmacotherapy is believed to be low and the characteristics and comorbidities that affect receipt are not well-established.

methodsWe created a dataset from Truven Health Analytics MarketScan Commercial Claims and Encounters Database of patients with an outpatient encounter for alcohol abuse or dependence in 2014. We subsequently identified patient characteristics, comorbid medical, psychiatric, or substance use disorders, as well as encounter provider specialties and, using multivariable logistic regression, assessed which variables correlated with increased or decreased receipt of pharmacotherapy for alcohol use disorder for this population.

resultsIn our dataset of 123,355 patients, patient receipt of pharmacotherapy for alcohol use disorder was 3.3 %, and 9.3 % when restricted to the former diagnosis of alcohol dependence only. Male sex, younger age, alcohol-related liver disease, and cannabis use disorders correlated with decreased receipt whereas comorbid major depressive disorders and anxiety disorders correlated with increased receipt. Compared to patients seen by psychiatrists, those seen by primary medical doctors had a lower odds of receiving pharmacotherapy.

conclusionsPharmacotherapy for alcohol use disorder is an underutilized treatment modality with a low prevalence of prescription in insured individuals. Patients with specific characteristics and comorbidities are less likely to receive this treatment and greater focus on these patients and in the primary care setting can allow for increased prescribing of these medications.

Indexed as

AdolescentAdultAlcoholismAnxiety DisordersComorbidityFemaleHumansMajor Depressive DisorderMaleMiddle AgedOutpatientsPrevalenceSubstance-Related DisordersAlcohol abuseAlcohol dependenceAlcohol use disorderComorbiditiesPharmacotherapy

Identifiers

PMID32721788
PMCPMC8011546
OpenAlexW3043255809

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.