Trial reportChest2020
Development of an Accurate Bedside Swallowing Evaluation Decision Tree Algorithm for Detecting Aspiration in Acute Respiratory Failure Survivors.
Trial report in Chest, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Aspiration in Acute Respiratory Failure Survivors
Aspiration in Acute Respiratory Failure Survivors
Who cites it
14 citing papers in PubMed, 31 citations in OpenAlex.
- Feasibility of Endoscopic Evaluations of Laryngeal Function After Extubation for Research in Critically Ill Adults.American journal of speech-language pathology · 2025Trial
- Assessment Tools for Intensive Care Unit-Acquired Dysphagia: A Network Meta-Analysis of Diagnostic Accuracy Studies.Dysphagia · 2026Review
- Identifying the association between post-extubation laryngeal edema and aspiration in acute respiratory failure patients.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Observational
- Risk factors for postextubation pneumonia using diagnosis procedure combination and claims data in Japan.Scientific reports · 2026Article
- The interdisciplinary fibreoptic endoscopic evaluation of swallowing assessments in ICU patients: A file review.The Southern African journal of critical care : the official journal of the Critical Care Society · 2026Article
- Post-intensive care syndrome: a state-of-the-art review.Singapore medical journal · 2026Review
- Developing a FEES service in South Africa: Interdisciplinary reflections for dysphagia care.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2025Article
- Post-extubation dysphagia in the ICU-a narrative review: epidemiology, mechanisms and clinical management (Update 2025).Critical care (London, England) · 2025Review
- Baseline 25-hydroxyvitamin D levels predict the effects of vitamin D supplementation on joint symptoms and cartilage loss in patients with knee osteoarthritis.Rheumatology advances in practice · 2025Article
- Risk stratification of thymic epithelial tumors based on peritumor CT radiomics and semantic features.Insights into imaging · 2024Article
- Perspective on dysphagia screening, assessment methods, and protocols in intensive care units: an opinion article.Frontiers in human neuroscience · 2024Article
- Dysphagia in Intensive Care Evaluation (DICE): An International Cross-Sectional Survey.Dysphagia · 2022Article
- [Postextubation dysphagia in intensive care patients : Current findings and clinical recommendations].Die Anaesthesiologie · 2022Review
- Addressing the post-acute sequelae of SARS-CoV-2 infection: a multidisciplinary model of care.The Lancet. Respiratory medicine · 2021Review
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Authors and funding
16 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundThe bedside swallowing evaluation (BSE) is an assessment of swallowing function and airway safety during swallowing. After extubation, the BSE often is used to identify the risk of aspiration in acute respiratory failure (ARF) survivors. RESEARCH QUESTION: We conducted a multicenter prospective study of ARF survivors to determine the accuracy of the BSE and to develop a decision tree algorithm to identify aspiration risk. STUDY DESIGN AND
methodsPatients extubated after ≥ 48 hours of mechanical ventilation were eligible. Study procedures included the BSE followed by a gold standard evaluation, the flexible endoscopic evaluation of swallowing (FEES).
resultsOverall, 213 patients were included in the final analysis. Median time from extubation to BSE was 25 hours (interquartile range, 21-45 hours). The FEES was completed 1 hour after the BSE (interquartile range, 0.5-2 hours). A total of 33% (70/213; 95% CI, 26.6%-39.2%) of patients aspirated on at least one FEES bolus consistency test. Thin liquids were the most commonly aspirated consistency: 27% (54/197; 95% CI, 21%-34%). The BSE detected any aspiration with an accuracy of 52% (95% CI, 45%-58%), a sensitivity of 83% (95% CI, 74%-92%), and negative predictive value (NPV) of 81% (95% CI, 72%-91%). Using recursive partitioning analyses, a five-variable BSE-based decision tree algorithm was developed that improved the detection of aspiration with an accuracy of 81% (95% CI, 75%-87%), sensitivity of 95% (95% CI, 90%-98%), and NPV of 97% (95% CI, 95%-99%).
interpretationThe BSE demonstrates variable accuracy to identify patients at high risk for aspiration. Our decision tree algorithm may enhance the BSE and may be used to identify patients at high risk for aspiration, yet requires further validation. TRIAL REGISTRY: ClinicalTrials.gov; No.: NCT02363686; URL: www.clinicaltrials.gov.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.